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Book Cover

Title Radiosurgery and pathological fundamentals / volume editors, G.T. Szeifert [and others]
Published Basel ; New York : Karger, ©2007


Description 1 online resource (xxxii, 399 pages) : illustrations (some color)
Series Progress in neurological surgery, 0079-6492 ; v. 20
Progress in neurological surgery ; v. 20. 0079-6492
Contents Cover -- Editor -- Co-Editors -- List of Contributors -- Contents -- In Memoriam Prof. Lars Leksell (1907 �1986) -- Acknowledgement -- Foreword -- Preface -- Prologue -- Gamma Knife �The Early Story: Memoirs of a Privileged Man -- Snapshots -- Methodological Progress -- (1)The Attachment -- (2)Individual Adjustments of Radiation Parameters -- (3)Treatment Nomogram -- (4)GK �The Second Generation -- Concluding Reflections -- References -- Chapter 1 -- Introduction:The Contribution of Pathology to Radiosurgery -- Abstract
Historical AntecedentsPathological Fundamentals -- Quo Vadis? -- Conclusions -- Acknowledgement -- References -- Chapter 2 -- Radiobiology of Radiosurgery -- Abstract -- The Effect of Dose Rate -- Experimental Laboratory Comparisons between Radiosurgery and Fractionation -- The Issue of Dose Homogeneity -- Benign Tumor Radiosurgery -- Vascular Effects -- Functional Radiosurgery -- Potential Pharmacologic Radioprotection for Radiosurgery -- References -- Chapter 3 -- Dose Selection in Stereotactic Radiosurgery -- Abstract -- Basic Principles
Treatment Planning and �Minimum�Tumor DoseDose-Volume Effects for Complications -- Early Dose-Volume Guidelines for Brain Tolerance -- Brain Tolerance Studies from AVM Radiosurgery -- Location Effects and AVM Radiosurgery Tolerance -- Cranial Nerve Tolerance to Radiosurgery -- The RTOG Phase I Maximum Tolerated Doses -- Target or Tumor Dose-Response Curves -- Functional Radiosurgery -- Arteriovenous Malformations -- Malignant Tumors -- References -- Chapter 4 -- Medical Physics Principles of Radiosurgery -- Abstract -- Ionizing Radiation
Clinical Beams for RadiosurgeryRadiosurgery Principles -- Dose-Volume Histograms and Indices -- References -- Chapter 5 -- Radiosurgery echniques and Current Devices -- Abstract -- Historical Review -- Gamma Knife Radiosurgery -- Charged-Particle Radiosurgery -- LINAC Radiosurgery -- Current Radiosurgical echniques -- Gamma Knife (Models A, B, C, 4-C, and PFX®) -- Rotating Gamma System -- LINAC-Based Radiosurgery -- Charged Particle Radiosurgery -- Spinal and Body Radiosurgery -- Radiosurgery Team -- Terms Used for Radiosurgery
Radiosurgery ProcedureDaily Quality Assurance of Radiosurgery System -- Application of the Stereotactic Guiding Device -- Techniques of Stereotactic Imaging -- Stereotactic MRI -- Stereotactic CT Imaging -- Stereotactic Angiography -- Determination of Target Volume -- Techniques of Conformal Dose Planning -- Techniques of Stereotactic Radiation Delivery Using Gamma Knife -- Conclusion -- References -- Chapter 6 -- Integration of Functional Imaging in Radiosurgery:The Example of PET Scan -- Abstract -- Materials and Methods -- Results -- Discussion
Summary Because of the huge clinical experience that has been accumulated in radiosurgery, it seems timely to explore and process out systematically pathological fundamentals on the effect of focused irradiation. The better understanding of radiobiology will enhance the outcomes of radiosurgical procedures. Renowned experts from all over the world discuss the baselines of pathology and radiobiology, medical physical principles, dose prescription guidelines, current radiosurgical techniques, advanced computer technology and recent imaging methods in radiosurgery. In this unique volume the most pioneering feature is the parallel discussion of clinical radiosurgical results with fundamental pathological findings following high-dose focused irradiation. Topics range from benign and malignant brain tumors, vascular malformations, functional disorders, ocular and spinal radiosurgery, interstitial brachytherapy to experimental efforts. This publication gives neurosurgeons, radiosurgeons, radiologists, pathologists, medical physicists, neurologists, oncologists, ophthalmologists, otolaryngologists as well as nuclear medicine and medical information technology experts an excellent understanding of the latest development of pathological fundamentals and new trends in radiosurgery
Bibliography Includes bibliographical references and indexes
Notes Print version record
Subject Radiosurgery.
Pathology, Surgical.
Radiosurgery -- methods
Pathology, Surgical
Brain Diseases -- surgery
Brain -- pathology
MEDICAL -- Surgery -- Neurosurgery.
Pathology, Surgical
Stereotaktische Hirnoperation -- Interventionsradiologie -- Aufsatzsammlung.
Interventionsradiologie -- Stereotaktische Hirnoperation -- Aufsatzsammlung.
Form Electronic book
Author Szeifert, G. T. (György T.)
ISBN 9783318014167