| Description |
1 online resource (xi, 230 pages) : illustrations (some color) |
| Series |
Methods in molecular biology, 1940-6029 ; volume 1831 |
|
Methods in molecular biology (Clifton, N.J.) ; v. 1831. 1064-3745
|
| Contents |
Synthesis of cationic polymer libraries for gene delivery using diglycidyl ethers / Jacob Elmer, Thrimoorthy Potta, and Kaushal Rege-- Generation of ultra-small PLGA nanoparticles by aequential centrifugation / Xingwang Wu, Jiangbing Zhou, and Toral R. Patel -- Construction of bacteria-based cargo carriers for targeted cancer therapy / Mahama A. Traore, Ali Sahari, and Bahareh Behkam -- Production of extracellular vesicles loaded with therapeutic cargo / Tek N. Lamichhane and Steven M. Jay -- Delivery of cytotoxic mesenchymal stem cells with biodegradable scaffolds for treatment of postoperative brain cancer / Kevin T. Sheets, Juli R. Bagó, and Shawn D. Hingtgen -- Nanoparticles for targeted drug delivery to cancer stem cells and tumor / Hai Wang and Xiaoming He -- Exploiting phage display for development of novel cellular targeting strategies / William Marsh, Amanda Witten, and Sarah E. Stabenfeldt -- CD44 targeted lipid nanoparticles for MicroRNA therapy / Stephen L. Hayward and Srivatsan Kidambi -- Ultrasound and microbubble-mediated blood-brain barrier disruption for targeted delivery of therapeutics to the brain / Meaghan A. O'Reilly and Kullervo Hynynen -- In vitro validation of targeting and comparison to mathematical modeling / Jill M. Steinbach-Rankins and Michael R. Caplan -- Enzyme-linked immunosorbent assay to quantify targeting molecules on nanoparticles / Rachel S. Riley, Jilian R. Melamed, and Emily S. Day -- Tunable collagen microfluidic platform to study nanoparticle transport in the tumor microenvironment / Matthew R. DeWitt and M. Nichole Rylander -- Utilizing the lung as a model to study nanoparticle-based drug delivery systems / Dylan K. McDaniel, Veronica M. Ringel-Scaia, Sheryl L. Coutermarsh-Ott, and Irving C. Allen -- Non-enzymatic tissue homogenization for biodistribution analysis / Danielle M. DiPerna, Alesia V. Prakapenka, Eugene P. Chung, and Rachael W. Sirianni -- Methods and study designs for characterizing the pharmacokinetics and pharmacodynamics of carrier-mediated agents / Allison N. Schorzman, Andrew T. Lucas, John R. Kagel, and William C. Zamboni |
| Summary |
This volume looks at the latest techniques used to enable therapeutic molecules to be targeted for site-specific delivery. The chapters in this book discuss topics such as approaches to express biologically derived and synthetic nanocarriers; strategies to assist in nanocarrier targeting to specific cells and tissues; and methods for evaluating delivery and efficiency for new classes of agents. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Targeted Drug Delivery: Methods and Protocols is a valuable resource for anyone interested in understanding the diversity of methods used in this evolving field |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Online resource; title from PDF title page (SpringerLink, viewed July 31, 2018) |
| Subject |
Drug delivery systems -- Laboratory manuals
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Drugs -- Administration.
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Drug Delivery Systems
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Drug Administration Routes
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Pharmacology.
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Medical -- Pharmacology.
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Drugs -- Administration
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Drug delivery systems
|
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Nanomedicina.
|
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Biologia molecular.
|
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Manuals de laboratori.
|
| Genre/Form |
Laboratory manuals
|
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Laboratory manuals.
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Manuels de laboratoire.
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Llibres electrònics.
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| Form |
Electronic book
|
| Author |
Sirianni, Rachael W., editor
|
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Behkam, Bahareh, editor
|
| ISBN |
9781493986613 |
|
1493986619 |
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