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E-book

Title Liver radioembolization with ⁹⁰Y microspheres / J.I. Bilbao and M.F. Reiser (eds.) ; with contributions by A. Alonso-Burgos [and others]
Published Berlin : Springer, ©2008

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Description 1 online resource (xii, 163 pages) : illustrations
Series Medical radiology : diagnostic imaging, 0942-5373
Medical radiology (Series)
Contents ⁹⁰Y Microspheres: concepts and principles / Andrew S. Kennedy, William A. Dezarn and Patrick McNeillie -- Identification of candidates and selection criteria / Ralf-Thorsten Hoffmann, Tobias F. Jakobs and Maximilian F. Reiser -- Radiological evaluation of patients with liver tumors / Christoph J. Zech and Maximilian F. Reiser -- Vascular anatomy and its implication in radioembolization / Antonio Martínez de la Cuesta, Alberto Alonso-Burgos, Isabel Vivas, Riad Salem and Jose I Bilbao -- Radioembolization : identifying and managing anatomic variants / Riad Salem, Robert J. Lewandowski, Robert K. Ryu, Kent Sato and Antonio Martinez de la Cuesta -- Posimetry and dose calculation / Andrew S. Kennedy, William A. Dezarn and Patrick McNeillie -- Improving treatment design by image fusion techniques / José F. Boán, Marta Valero and Javier Arbizu -- Nuclear medicine procedures for treatment evaluation / W. Koch and K. Tatsch -- Radiological detection and assessment of tumor response / Tobias F. Jakobs -- Results in hepatocellular carcinoma / Mercedes Iñarrairaegui and Bruno Sangro -- Results in liver metastatic colorectal cancer / Andrew S. Kennedy, William A. Dezarn and Patrick McNeillie -- 90Y Microspheres for other liver metastases / Javier Rodriguez, Ana Chopitea, Antonio Viudez and Jesús Garcia-Foncillas -- Use of ⁹⁰Y SIR-spheres in the treatment of unresectable hepatic metastases from neuroendocrine tumors / Douglas M. Coldwell, Andrew S. Kennedy and Charles Nutting -- Complications and side effects / Ralf-Thorsten Hoffman, José I. Bilbao, Tobias F. Jakobs, Lourdes Diaz-Dorronsoro, Laurent Desloques and Maximilian F. Reiser -- Future directions in radioembolization / Riad Salem, Saad Ibrahim, Bassel Atassi and Robert J. Lewandowski
Summary This book provides an in-depth account of all aspects of radioembolization, a relatively novel technique based on the efficacy of radiotherapy for the treatment of liver tumors. In the past, the therapeutic radiation dose needed to treat a tumoral area has been sufficiently high to produce permanent damage to the nontumoral liver parenchyma. Radioembolization attempts to overcome this problem by combining embolization (intravascular deployment of particles) and brachytherapy (local administration of radiotherapy with the aid of a device, namely the particles themselves). The technique is based on improvements in percutaneous endovascular procedures which have allowed the deployment of small (25-35 [micro]m) microspheres loaded with yttrium-90 that deliver high doses of beta-radiation specifically to the tumoral area. Performance of the procedure demands close familiarity with the hepatic vascular anatomy in order to ensure avoidance of vessels going to other territories. Furthermore, detailed knowledge of liver function, tumor volume, and liver vascular shunting is needed in order to calculate the appropriate therapeutic dose in each particular case. All of these topics are addressed in depth in this book, and initial clinical results are presented, showing that constant local control can be achieved with a reasonably low rate of complications. These promising results may lead to a progressive change in the therapeutic indication for radioembolization, and in some cases it could even become the therapy of choice
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Liver -- Cancer -- Treatment
Therapeutic embolization.
Radioisotope brachytherapy.
Liver Neoplasms -- radiotherapy
Embolization, Therapeutic
Brachytherapy
Brachytherapy -- methods
Embolization, Therapeutic -- methods
MEDICAL -- Oncology.
HEALTH & FITNESS -- Diseases -- Cancer.
Liver -- Cancer -- Treatment
Radioisotope brachytherapy
Therapeutic embolization
Form Electronic book
Author Bilbao, J. I. (José I.)
Reiser, Maximilian.
Alonso-Burgos, A
ISBN 9783540354239
3540354239