Title Multiple sclerosis : bench to bedside : global perspectives on a silent killer / Alexander A.A. Asea, Fabiana Geraci, Punit Kaur, editors

Published Cham, Switzerland : Springer, [2017] ©2017

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Description 1 online resource (viii, 188 pages) : illustations (some color) Series Advances in experimental medicine and biology, 2214-8019 ; volume 958 Advances in experimental medicine and biology ; v. 958. 0065-2598 Contents Extracellular vesicles in multiple sclerosis as possible biomarkers: dream or reality? / Maria Magdalena Barreca, Emanuele Aliotta, Fabiana Geraci -- Manipulation of oxygen and endoplasmic reticulum stress factors as possible interventions for treatment of multiple sclerosis: evidence for and against / Paul Eggleton, Gary R. Smerdon, Janet E. Holley, Nicholas J. Gutowski -- Heat shock proteins in multiple sclerosis / Ortan Pinar, Yildirim Akan Ozden, Erkizan Omur, Gedizlioglu Muhtesem -- Meaning of self in multiple sclerosis: implications for treatment and rehabilitation / Maciej Wilski, Tomasz Tasiemski -- Multiple sclerosis and EIF2B5: a paradox or a missing link / Insha Zahoor, Ehtishamul Haq, Ravouf Asimi -- Molecular genetic and epigenetic basis of multiple sclerosis / Zohreh Hojati -- Role of oligodendrocyte dysfunction in demyelination, remyelination and neurodegeneration in multiple sclerosis / Adriana Octaviana Dulamea -- Clinical neurophysiology of multiple sclerosis / Mario Habek, Ivan Adamec, Barbara Barun, Luka Crnošija, Tereza Gabelić, Magdalena Krbot Skorić -- Multiple sclerosis epidemiology in europe / Daiana Bezzini, Mario A. Battaglia -- Timing of future remyelination therapies and their potential to stop multiple sclerosis progression / Burcu Zeydan, Moses Rodriguez, Orhun H. Kantarci -- Neuroplasticity-based technologies and interventions for restoring motor functions in multiple sclerosis / Sofia Straudi, Nino Basaglia Summary "Multiple Sclerosis (MS) is one of the main causes of disability in young adult population. The estimated burden of the disease worldwide is about three million people. The pathogenic mechanism of MS involves both auto immune and degenerative processes. These two mechanisms are thought to determine a combination of events leading to several clinical pattern of disease onset and course. Multiple Sclerosis: Bench to Bedside provides the most up-to-date and concise reviews on the critical issues of multiple sclerosis from around the world. This book is written by leaders and experts in the field of multiple sclerosis research and is divided into easy to read sections. Section I focuses on basic science aspects of Multiple Sclerosis, including potential biomarkers, molecular biology, heat shock proteins, oxidative stress, genetic and epigenetics. Section II focuses on clinical and epidemiological aspects of Multiple Sclerosis, including remyelination therapy, neuroplasticity-based technologies and interventions. This is an important reference book and a must-read for Postgraduate Medical Scholars, Basic Science Researchers and Neurologists in Clinical Practice"--Publisher's description Bibliography Includes bibliographical references and index Notes Online resource; title from pdf title page (SpringerLink, viewed January 31, 2017) In Springer eBooks Subject Multiple sclerosis. Multiple Sclerosis MEDICAL -- Neurology. MEDICAL -- Diseases. Multiple sclerosis Form Electronic book Author Asea, Alexzander A. A., editor. Geraci, Fabiana, editor Kaur, Punit, editor. ISBN 9783319478616 3319478613

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