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Book Cover
E-book

Title Zebrafish protocols for neurobehavioral research / edited by Allan V. Kalueff, Adam Michael Stewart
Published New York : Springer : Humana Press, ©2012

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Description 1 online resource (xvii, 357 pages) : illustrations (some color)
Series Neuromethods, 1940-6045 ; v. 66
Neuromethods ; v. 66. 0893-2336
Contents Measuring larval Zebrafish behavior : locomotion, thigmotaxis, and startle / William H.J. Norton -- Light-dark preference test for larval Zebrafish / Peter J. Steenbergen, Michael K. Richardson, and Danielle L. Champagne -- Assessment of thigmotaxis in larval Zebrafish / Stephanie J. Schnörr [and others] -- Zebrafish and drug development : a behavioral assay system for probing nicotine function in larval Zebrafish / Henning Schneider [and others] -- Olfactory-evoked activity assay for larval Zebrafish / Ganive Bhinder and Keith B. Tierney -- Qualitative and quantitative measurements of the optokinetic response in larval Zebrafish / Kaspar P. Mueller and Stephan C.F. Neuhauss -- Automated imaging of visual recognition memory in larval Zebrafish / Ruth M. Colwill and Robbert Creton -- Automated conditioning in larval Zebrafish / Ruey-Kuang Cheng and Suresh Jesuthasan -- Methods to quantify basal and stress-induced cortisol response in larval Zebrafish / Peter J. Steenbergen [and others] -- Method for sorting Zebrafish on the exploratory-bold behavioral axis / Cory D. Sailer, Sonny J. Radenic, and Brian D. Wisenden -- Nocifensive behavior in adult and larval Zebrafish / Monica Gomes Lima [and others] -- Use of a split depth and visual cliff apparatus to measure the diving response in Zebrafish / Rachel Blaser and Kelly Goldsteinholm -- Adapting the open field test to assess anxiety-related behavior in Zebrafish / John Godwin [and others] -- Behavioral and pharmacological aspects of anxiety in the light/dark preference test / Juliana Araujo [and others] -- High-throughput and inexpensive assay for anxiety-related behaviors in the Zebrafish, based on place preference and latency to feed / Barrie D. Robison [and others] -- Automated Tracking of Zebrafish shoals and the analysis of shoaling behavior / Noam Miller and Robert Gerlai -- Assessing social behavior phenotypes in adult Zebrafish : shoaling, social preference, and mirror biting tests / Mimi Pham [and others] -- Measuring effects of psychostimulants on egocentric spatial learning and memory in adult Zebrafish / Rabia Nasir [and others] -- Cued fear conditioning in Zebrafish (Danio rerio) / Masakazu Agetsuma [and others] -- Assessing learning and memory through the active avoidance paradigm / Xiaojuan Xu and Stefan Goetz -- Assessing habituation phenotypes in adult Zebrafish : intra- and inter-trial habituation in the novel tank test / Jolia Raymond [and others] -- Assessing startle responses and their habituation in adult Zebrafish / Simon Chanin [and others] -- QTL mapping using behavioral traits in the adult Zebrafish / Dominic Wright -- Assessing epilepsy-related behavioral phenotypes in adult Zebrafish / Daniel Desmond [and others] -- Rapid method for acute intracerebroventricular injection in adult Zebrafish / Augusto Barbosa Júnior [and others] -- Western blotting assay for Egr-1 immediate early gene in brain tissue of Zebrafish applied to neuroethological study / Augusto Barbosa Júnior [and others] -- Utilizing the Zebrafish neurophenome project (ZNP) database for analyses of complex neurophenotypes in Zebrafish models / Ivan Zapolsky [and others]
Summary Zebrafish (Danio rerio) play an integral role in biomedical research, enabling researchers to examine physiological mechanisms and pathways relevant to human pathogenesis and its therapy. That, along with their low cost, easy manipulation, short reproductive cycles, and physiological homology to humans, has made zebrafish a vital model organism for neuroscience research. Zebrafish Protocols for Neurobehavioral Research addresses protocols for both larval and adult models, written by the leading experts in the field of zebrafish research. Part I of this book takes advantage of the high-throughput nature of larval models to offer protocols for research requiring high output, easily manipulated screens. The second half of the book focuses on the robust and sophisticated behaviors of adult zebrafish, suitable for the neurophenotyping of complex traits and multi-domain disorders. Importantly, these models complement each other, working together to provide researchers with valuable insights into neurobiology of normal and pathological behavior. Thorough and cutting-edge, this volume is a useful, authoritative reference guide that should hold a coveted spot in zebrafish laboratories across the globe
Analysis biomedische wetenschappen
biomedicine
neurowetenschap
neuroscience
diermodellen
animal models
Medicine (General)
Geneeskunde (algemeen)
Bibliography Includes bibliographical references and index
Notes English
Print version record
Subject Logperch -- Behavior
Zebra danio.
Neurobehavioral disorders -- Research
Zebrafish
Models, Animal
Behavioral Research
Neurobehavioral Manifestations
Zebra danio
Genre/Form Laboratory manuals
Laboratory manuals.
Manuels de laboratoire.
Form Electronic book
Author Kalueff, Allan V., editor.
Stewart, Adam Michael, editor
ISBN 9781617795978
1617795976