Title Selenium : Chemistry, Analysis, Function and Effects / edited by Victor R. Preedy

Published Cambridge : Royal Society of Chemistry, 2015

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Description 1 online resource (667 pages) Series Food and Nutritional Components in Focus, 2045-1695 Food and nutritional components in focus. 2045-1695 Contents Cover; Selenium Chemistry, Analysis, Function and Effects ; Preface; Section I Chemistry and Biochemistry ; Chapter 1 -- The Chemistry of Selenium; 1.1 Chemical Properties of Selenium; 1.2 Organoselenium Compounds; 1.3 Selenium in Soil and Foods; Summary Points; Keys Facts of Seleno proteins ; Definitions and Explanations of Key Terms; List of Abbreviations; References; Chapter 2 -- Biochemistry and Molecular Biology of Selenoproteins; 2.1 Selenoproteins in Mammals; 2.1.1 Thioredoxin Reductases; 2.1.2 Glutathione Peroxidases; 2.1.3 Selenoprotein P; 2.1.4 Selenoprotein N 2.1.5 Iodothyronine Deiodinases2.1.6 Selenoprotein R is a Methionine-Sulfoxide-Reductase; 2.1.7 Selenoproteins Involved in Protein Biosynthesis, Folding or Degradation; 2.2 Selenoprotein Biosynthesis; 2.2.1 Biosynthesis of Selenocysteine; 2.2.1.1 Selenocysteine Biosynthesis Occurs on its tRNA; 2.2.1.2 Seryl-tRNA Synthetase (SerRS); 2.2.1.3 O-Phosphoseryl-tRNASec Kinase (PSTK); 2.2.1.4 Selenocysteine Synthetase (SepSecS); 2.2.1.5 Selenophosphate Synthetases; 2.2.2 Translation of Selenoproteins; 2.2.2.1 The Hierarchy of Selenoproteins; 2.2.2.2 SECIS-Binding Protein 2 (SECISBP2) 2.2.2.3 Sec-Specific Eukaryotic Elongation Factor (EFSec)2.2.2.4 SECp43; 2.2.2.5 Selenocysteine Insertion Sequence (SECIS) Element; 2.2.2.6 Selenocysteine Redefinition Element (SRE); 2.2.2.7 tRNA[Ser]Sec; Summary Points; Key Facts: Recoding of UGA; Key Facts: Mutations in SECISBP2; Definitions; List of Abbreviations; References; Chapter 3 Synthesis of Organoselenium Derivatives of Biological Relevance ; 3.1 Introduction; 3.2 Isoselenocyanates and Related Selenoxo Compounds ; 3.3 Selenosugars; 3.4 Ebselen and Derivatives; 3.5 Miscellaneous; Summary Points; Key Facts Definitions of Words and TermsList of Abbreviations; Acknowledgements; References; Chapter 4 -- Chemistry and Activity of Selenium Dioxide and Selenite Ions; 4.1 Introduction; 4.2 Oxidation State and Speciation in Aqueous Solution; 4.3 SeO32− as a Nutritional Supplement; 4.4 Pro-Oxidant Behavior; 4.4.1 Oxidative Activity of SeO2; 4.4.2 ROS Formation and SeO32−; 4.4.3 Chemopreventive and Chemotherapeutic Activity of SeO32−; 4.5 Interactions with Metal Ions; 4.5.1 Role of SeO32− in Mediating Metal Toxicity; 4.5.2 SeO2 and SeO32− as Antioxidants; 4.6 Conclusion; Summary Points; Key Facts Definitions and Explanation of Key TermsList of Abbreviations; References; Chapter 5 -- Chemistry and Biochemistry: Selenium Species in Fish; 5.1 Background; 5.2 Selenoproteins; 5.3 Low Molecular Mass Organoselenium Compounds; 5.4 Conclusions; Summary Points; Key Facts; Key Facts of Selenoprotein L (SelL); Key Facts of Fish 15 kDa Selenoprotein-like Protein (Fep15); Definitions of Words and Terms; List of Abbreviations; References; Section II Analysis ; Chapter 6 -- Current Analytical Strategies and Techniques Related to Selenoproteins in Foods ; 6.1 Introduction; 6.1.1 Selenoproteins in Food Summary This volume will examine the chemical activity of selenium and its functional health effects eg towards cancers, in the heart and brain. Chemists, analytical scientists, forensic scientists, food scientists, as well as course lecturers will all benefit from this interdisciplinary title written by international experts in this area Notes 6.2 The Role of ICP-MS in Selenoproteins Speciation Bibliography Includes bibliographical references at the end of each chapters and index Notes English Print version of record Subject Selenium in human nutrition -- Physiological effect Selenium. Trace elements. Dietary supplements. Physiology. Enriched foods. Pharmacology. Chalcogens. Minerals. Life sciences. Food. Inorganic compounds. Physical sciences. Chemical elements. Growth factors. Selenium Trace Elements Dietary Supplements Physiology Food, Fortified Pharmacology Chalcogens Minerals Micronutrients Biological Science Disciplines Foods, Specialized Food Inorganic Chemicals Natural Science Disciplines Elements Food and Beverages Growth Substances Physiological Effects of Drugs Disciplines and Occupations Technology, Industry, Agriculture Chemicals and Drugs Pharmacologic Actions Chemical Actions and Uses selenium. trace elements. physiology. pharmacology. mineral. biological sciences. food. physical sciences. elements (chemical substances) Chemistry. Food & beverage technology. TECHNOLOGY & ENGINEERING -- Food Science. SCIENCE -- Chemistry -- Analytic. Trace elements Physiology Physical sciences Pharmacology Minerals Life sciences Inorganic compounds Growth factors Food Enriched foods Dietary supplements Chemical elements Chalcogens Selenium Form Electronic book Author Preedy, Victor R., editor. ISBN 1849738912 9781849738910 9781782622215 1782622217

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