Title Computational advances in bio and medical sciences : 11th international conference, ICCABS 2021, virtual event, December 16-18, 2021, revised selected papers / Mukul S. Bansal, Ion Măndoiu, Marmar Moussa, Murray Patterson, Sanguthevar Rajesekaran, Pavel Skums, Alexander Zelikovsky (eds.)

Published Cham : Springer, [2022] ©2022

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Description 1 online resource (x, 177 pages) : illustrations (chiefly color) Series Lecture notes in computer science. Lecture notes in bioinformatics ; 13254 LNCS sublibrary: SL8 - Bioinformatics Lecture notes in computer science ; 13254. Lecture notes in computer science. Lecture notes in bioinformatics. LNCS sublibrary. SL 8, Bioinformatics. Contents Intro -- Preface -- Organization -- Contents -- Computational Advances in Bio and Medical Sciences -- Single Model Quality Estimation of Protein Structures via Non-negative Tensor Factorization -- 1 Introduction -- 2 Related Works -- 3 Methodology -- 3.1 Stage I: From Structures to Groups -- 3.2 Stage II: Ranking Groups -- 3.3 Stage III: Partitioning Groups into Subgroups -- 3.4 Stage IV: Scoring Each Structure -- 3.5 Experimental Setup -- 3.6 Dataset -- 3.7 Evaluation Metrics -- 4 Results -- 4.1 Comparative Evaluation on Correlation with TM-Score -- 4.2 Loss-Based Comparison 4.3 Statistical Significance Analysis -- 5 Conclusion -- References -- Graph Representation Learning for Protein Conformation Sampling -- 1 Introduction -- 1.1 Related Work -- 2 Methods -- 3 Results -- 3.1 Experimental Setup -- 3.2 Evaluation of Models on Fixed-Length Chains -- 3.3 Evaluation of Models on Variable-Length Chains -- 4 Conclusion -- References -- Excerno: Filtering Mutations Caused by the Clinical Archival Process in Sequencing Data -- 1 Introduction -- 2 Excerno: A Bayes Classifier Using Mutational Signatures -- 3 Simulation and Evaluation Approach -- 4 Simulation Results 4.1 Performance Characteristics Across Different COSMIC Baseline Signatures -- 4.2 Performance Characteristics Across Different Percentages of FFPE -- 5 Conclusions -- References -- Relabeling Metabolic Pathway Data with Groups to Improve Prediction Outcomes -- 1 Introduction -- 2 Method -- 2.1 Feed-Forward Phase -- 2.2 Feed-Backward Phase -- 2.3 Closing the Loop -- 3 Experiments -- 3.1 Accumulated History Probability Analysis -- 3.2 Metabolic Pathway Prediction -- 4 Conclusion -- References -- MELEPS: Multiple Expert Linear Epitope Prediction System -- 1 Introduction -- 2 Materials and Methods 2.1 Data Collection -- 2.2 The System Flow of MELEPS -- 2.3 Integrated Multi-expert Recommendation Methodology -- 2.4 The Weighted Recommendation Score -- 2.5 Performance Measurement of Recommendation -- 3 Results and Discussion -- 3.1 The Weight Parameter Table -- 3.2 Performance of MELEPS -- 3.3 The MELEPS Platform -- 4 Conclusion -- References -- Encoder-Decoder Architectures for Clinically Relevant Coronary Artery Segmentation -- 1 Introduction -- 2 Related Work -- 2.1 Major Vessel Segmentation -- 2.2 Full Coronary Tree Segmentation -- 2.3 Catheter and Full Coronary Tree Segmentation 2.4 Other Segmentation Criteria -- 3 Model Evaluation Metrics -- 4 Loss Function -- 5 Architecture -- 5.1 Encoder Comparison -- 5.2 Decoder Comparison -- 5.3 EfficientUNet++ Architecture -- 5.4 Performance vs. Computation Trade-Off -- 6 Experimental Results -- 7 Implementation Details -- 7.1 Training Methodology -- 7.2 Dataset -- 7.3 Data Augmentation -- 8 Discussion and Future Work -- References -- Unified SAT-Solving for Hard Problems of Phylogenetic Network Construction -- 1 Introduction: Evolutionary Trees and Phylogenetic Networks -- 2 Definitions and Problem Statements Summary This book constitutes revised selected papers from the refereed proceedings of the 11th International Conference on Computational Advances in Bio and Medical Sciences, ICCABS 2021, held as a virtual event during December 16-18, 2021. The 13 full papers included in this book were carefully reviewed and selected from 17 submissions. They were organized in topical sections as follows: Computational advances in bio and medical sciences; and computational advances in molecular epidemiology Notes Selected conference papers Includes author index Online resource; title from PDF title page (SpringerLink, viewed November 1, 2022) Subject Bioinformatics -- Congresses Medical informatics -- Congresses Bioinformatics Medical informatics Genre/Form proceedings (reports) Conference papers and proceedings Conference papers and proceedings. Actes de congrès. Form Electronic book Author Bansal, Mukul S., editor Măndoiu, Ion, editor. Moussa, Marmar, editor Patterson, Murray, editor Rajasekaran, Sanguthevar, editor. Skums, Pavel, editor. Zelikovsky, Alexander, editor. ISBN 9783031175312 303117531X 9788303117533 830311753X

Other Titles ICCABS 2021

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