| Description |
1 online resource (466 pages) ; illustrations |
| Contents |
Intro -- Preface -- Contents -- About the Editors -- 1: Nanotechnology: Application in Biology and Medicine -- 1.1 Introduction -- 1.2 History of Nanotechnology -- 1.3 Definition -- 1.4 Importance of Size -- 1.5 Applications in Biology and Medicine -- 1.6 Applications in Biology -- 1.6.1 Bioseparation: Separation and Purification of Biological Molecules -- 1.6.1.1 Separation of DNA -- 1.6.1.2 Separation of Proteins -- 1.6.1.3 Separation of Biomolecules -- 1.6.2 Probing of DNA Structure -- 1.6.3 Fluorescent Biological Labels -- 1.6.4 Biological Processes |
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1.6.5 Biosensing with Magnetic Nanoswitches -- 1.6.6 Single Cell Phenotypes -- 1.6.7 Delivery Vehicles -- 1.6.7.1 Delivering Hydrophobic Compounds Without Solvents -- 1.6.7.2 Delivering siRNA for Biological Studies -- 1.6.7.3 Delivering Agents to Subcellular Organelles -- 1.7 Applications in Medicine -- 1.7.1 Drug Delivery -- 1.7.2 Diagnostic Applications -- 1.7.2.1 Quantum Dots -- 1.7.2.2 Gold Nanoparticles -- 1.7.3 Cardiac Therapy -- 1.7.4 Orthopedic Applications -- 1.7.5 Dentistry -- 1.7.6 Magnetic Resonance Imaging (MRI) -- 1.7.7 Cancer Therapy -- 1.7.8 Hyperthermia |
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1.7.9 Ophthalmology -- 1.7.10 Tissue Engineering -- 1.8 Conclusion -- References -- 2: Biological Activities of Nanoparticles and Mechanism of Action -- 2.1 Introduction -- 2.2 Green Synthesis of Nanoparticles -- 2.3 Interaction of NPs with Biological Components -- 2.4 Antibacterial Activity of Nanoparticles -- 2.5 Anticancer Activity of Nanoparticles -- 2.6 General Mechanism for Activity by Nanoparticles -- 2.6.1 Oxidative Stress -- 2.6.2 Nonoxidative Mechanism -- 2.6.3 Dissolved Metal Ions -- 2.7 Application of Metal NPs -- 2.7.1 Antimicrobial Application of NPs |
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2.7.2 Anticancer Application of NPs -- 2.8 Conclusion and Perspectives -- References -- 3: Application of Nanoparticles in Drug Delivery -- 3.1 Introduction -- 3.2 Nanoparticles -- 3.3 Antimicrobial Mechanism of NPs -- 3.4 Application of Silver Nanoparticles as an Antibacterial and Antifungal Agents -- 3.5 Application of Magnesium Oxide (MgO) and Calcium Oxide NPs (CaO) NPs as Antimicrobial Agents -- 3.6 Application of Silica NPs (SiO2) as Antimicrobial Agents -- 3.7 Application of Titanium Dioxide (TiO2) NPs as Antimicrobial Agents |
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3.8 Application of Zinc Oxide (ZnO) NPs as Antimicrobial Agents -- 3.9 Application of Iron Oxide (Fe3O4) NPs as Antimicrobial Agents -- 3.10 Application of Gold (Au) NPs as Antimicrobial Agents -- 3.11 Application of Copper Oxide (CuO) NPs as Antimicrobial Agents -- 3.12 Application of Aluminum (Al) NPs as Antimicrobial Agents -- 3.13 Application of Bismuth (Bi) NPs as Antimicrobial Agents -- 3.14 Application of Carbon-Based NPs as Antimicrobial Agents -- 3.15 Application of Organic NPs as Antimicrobial Agents -- 3.16 Application of Eco-friendly Green NPs as Antimicrobial Agents |
| Summary |
This book provides a comprehensive overview of state-of-the-art applications of nanotechnology in biology and medicine, as well as model organisms that can help us understand the biological activity and associated toxicity of nanoparticles, and devise strategies to minimize toxicity and enhance therapies. Thanks to their high surface-to-volume ratio, nanoparticles are characterized by excellent biocompatibility and bioavailability, a high therapeutic index, and relatively low toxicity, which has led to their widespread application in the early diagnosis of diseases, comprehensive monitoring of disease progression, and improved therapeutics. The book also explores nanoparticle-based insecticides and their mechanisms of action, and provides a comparative analysis of the various model organisms that are used to understand the biological properties of nanoparticles. Further, it describes various in-vivo models that yield important insights into nanomaterial-mediated toxicity, promoting the optimal utilization of nanoparticles. In closing, the book discusses future perspectives and regulatory issues concerning the use of nanomaterials in translational research |
| Bibliography |
Includes bibliographical references |
| Notes |
3.17 Application of NPs as Antiviral Agents |
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Print version record |
| Subject |
Nanoparticles -- Toxicology
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Animal models in research
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Human physiology
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Nanotechnology
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Pharmacology
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| Genre/Form |
Electronic books
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| Form |
Electronic book
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| Author |
Siddhardha, Busi.
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Dyavaiah, Madhu.
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Kasinathan, Kaviyarasu.
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| ISBN |
9789811517020 |
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9811517029 |
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