| Description |
1 online resource (270 p.) |
| Contents |
Intro -- Neurostimulation for Epilepsy: Advances, Applications, and Opportunities -- Copyright -- Contents -- Contributors -- Preface -- Acknowledgments -- Chapter 1 Principles of neurostimulation -- Introduction -- Technical and biophysical background of neurostimulation -- Targets for neurostimulation in epilepsy -- Antiepileptic effects of specific stimulus forms -- High-frequency stimulation (HFS) -- Low-Frequency Stimulation (LFS) -- DC stimulation -- Stimulation of peripheral nerves: Vagus nerve stimulation -- Stimulation of network hubs: Anterior and centromedian nuclei of the thalamus |
|
Combining neuromodulatory approaches -- Closed-loop stimulation -- Cognitive tolerability of therapeutic brain stimulation -- References -- Chapter 2 Neurostimulation device technology -- Introduction -- Neuromodulation technology -- Neural interface model -- Neural biosignal sensing -- Neural stimulation -- Limitation and safety -- Commercially available implantable neuromodulation devices for epilepsy -- Direction of future neuromodulation technology -- References -- Chapter 3 Vagus nerve stimulation -- Introduction -- History -- Efficacy -- Long-term clinical studies |
|
Postapproval long-term outcomes -- New features, pediatric, elderly, and special populations -- Mechanism of action -- Experimental studies -- Clinical studies -- Selection of candidates -- Initiation and maintenance -- Complications and adverse effects -- Advantages and disadvantages -- Future developments -- Addendum -- References -- Chapter 4 Responsive neurostimulation -- Theoretical underpinnings -- Temporal and spatial specificity -- Open- versus closed-loop stimulation -- Acute disruptive and long-term neuromodulatory effects -- RNS System -- Detection -- Electrocorticograms (ECoGs) |
|
Stimulation -- Trending -- Clinical data -- Pivotal trial -- Study design -- Results -- Safety -- Post hoc analyses of pivotal trial data -- Seven-year neocortical outcomes -- Seven-year mesial temporal outcomes -- Quality of life -- Neuropsychological outcomes -- Real-world trial -- Nine-year long-term extension data -- Utilization of long-term trending data -- Identification of intrinsic patient-specific variations -- Illustrate effects of other treatments -- Inform future surgeries -- Sudden unexpected death in epilepsy (SUDEP) -- MRI compatibility |
|
Practical considerations and troubleshooting -- High impedances during implantation -- High impedances at a return visit -- Side effects from stimulation -- Scalp EEG artifact -- Failure of seizures to respond adequately to standard stimulation parameters -- Targets for responsive neurostimulation -- Cortical RNS targets -- White matter targets -- Subcortical targets: Thalamic -- Subcortical targets: Thalamic-Anterior nucleus -- Subcortical targets: Thalamic-Centromedian nucleus -- Subcortical targets: Pulvinar -- Subcortical targets: Heterotopias -- Future directions -- Conclusions |
| Notes |
Description based upon print version of record |
|
Acknowledgments |
| Form |
Electronic book
|
| ISBN |
9780323985642 |
|
0323985645 |
|
