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Title Severe trauma and sepsis : organ damage and tissue repair / editors, Xiaobing Fu and Liangming Liu
Published Singapore : Springer, [2019]

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Description 1 online resource
Contents Intro; Preface; Contents; 1: Damage Control in Abdominal Compartment Syndrome; 1.1 Introduction; 1.2 Abdominal Compartment Syndrome; 1.2.1 Pathophysiology of ACS; 1.2.1.1 Pulmonary Dysfunction; 1.2.1.2 Cardiac Dysfunction; 1.2.1.3 Renal Dysfunction; 1.2.1.4 Gut and Liver Dysfunction; 1.2.2 Measurement of IAP; 1.3 Damage Control; 1.3.1 Initial Treatments; 1.3.2 Abbreviated Surgery; 1.3.3 Damage Control Resuscitation; 1.3.3.1 Permissive Hypotension; 1.3.3.2 Hemostatic Resuscitation; 1.4 Conclusion; References; 2: Damage Control Resuscitation; 2.1 Definition; 2.2 Background
2.3 Pathophysiology2.3.1 Hypothermia; 2.3.2 Acidosis; 2.3.3 Coagulopathy; 2.4 Damage Control Resuscitation; 2.4.1 Permissive Hypotension and Restrictive Fluid Administration; 2.4.2 Hemostatic Resuscitation; 2.4.3 Early Hemorrhage Control; 2.4.4 Correction of Acidosis; 2.4.5 Rewarming; 2.5 Conclusions; References; 3: Perioperative Intestinal Injury: Etiology, Mechanism, and Prevention; 3.1 Etiology of Perioperative Intestinal Injury; 3.1.1 Trauma and Shock; 3.1.2 Acute Pancreatitis; 3.1.3 Cardiac Surgery and Cardiopulmonary Bypass; 3.1.4 Abdominal Aortic Aneurysm (AAA) Repair
3.1.5 Liver Surgery3.1.6 Intestinal Transplantation; 3.1.7 Intestinal Diseases; 3.2 Mechanism of Perioperative Intestinal Injury; 3.2.1 Intestine Barrier Function Impairment; 3.2.1.1 Mechanical Barrier Function; 3.2.2 Immune Barrier Function; 3.2.2.1 Humoral Immune Function Impairment; 3.2.2.2 Cellular Immune Function Impairment; 3.2.3 Microbiota Barrier; 3.2.4 Chemical Barrier; 3.2.5 Remote Organ Damage Due to Intestinal Injury; 3.3 Prevention and Treatment; 3.3.1 Early Enteral Nutrition; 3.3.1.1 Glutamine (Gln); 3.3.1.2 Growth Factors; 3.3.2 Anti-oxyradical Agent
3.3.3 Traditional Chinese Medicine3.3.4 Anesthetics; 3.3.5 Antiendotoxin Therapy; 3.3.6 Ischemic Preconditioning/Postconditioning; 3.3.7 Stem Cell; 3.4 Conclusion; References; 4: The Role of Mitochondrial Quality Imbalance in Multiple Organ Dysfunction Syndrome Following Severe Trauma, Shock, and Sepsis; 4.1 Introduction; 4.2 Role of Mitochondrial Quality Imbalance in Diseases; 4.2.1 Role of Mitochondria Dysfunction in Various Diseases; 4.2.2 Mitochondrial Quality Balance Is a Dynamic Process to Regulate Mitochondrial Function; 4.2.2.1 Mitochondrial Fission
4.2.2.2 Mitochondrial Fusion4.2.2.3 Mitophagy; 4.2.2.4 Mitochondrial Biogenesis; 4.2.3 Role of Mitochondrial Quality Imbalance in Various Diseases; 4.3 Role of Mitochondrial Quality Imbalance in MODS Following Severe Trauma, Shock, and Sepsis; 4.3.1 Role of Mitochondrial Dysfunction in MODS Following Severe Trauma, Shock, and Sepsis; 4.3.2 Possible Role of Mitochondrial Quality Imbalance in MODS Following Severe Trauma, Shock, and Sepsis; 4.3.3 Cross Talk of Fission, Fusion, Mitophagy, and Biogenesis Regulates Organ Function
Summary This book discusses recent progress in organ damage and tissue repair following severe trauma and sepsis. In part 1, it introduces the theory and clinical practice in organ damage. In part 2, it covers all the subjects of sepsis, ranging from mechanism, inflammation, and infection to the lung injury and neonatal sepsis. In part 3, it discusses 4 new advances techniques in tissue repair. There are 20 chapters contributed by experts in each area. This book is a valuable reference for scientists and clinicians to know the new knowledge and technology in severe trauma and sepsis, which will benefit their work in research and clinic through multidisciplinary collaboration
Bibliography Includes bibliographical references
Notes Online resource; title from PDF title page (EBSCO, viewed June 3, 2019)
Subject Wounds and injuries.
Septicemia.
Wounds and Injuries
Sepsis
HEALTH & FITNESS -- Diseases -- General.
MEDICAL -- Clinical Medicine.
MEDICAL -- Diseases.
MEDICAL -- Evidence-Based Medicine.
MEDICAL -- Internal Medicine.
Septicemia
Wounds and injuries
Form Electronic book
Author Fu, Xiaobing, editor.
Liu, Liangming, M.D., editor.
ISBN 9789811333538
981133353X
9789811333545
9811333548