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Book Cover
E-book
Author Botana, Luis M

Title Phycotoxins : Chemistry and Biochemistry
Edition 2nd ed
Published Hoboken : Wiley, 2015

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Description 1 online resource (1449 pages)
Contents Cover; Table of Contents; Title Page; Copyright; List of contributors; Preface; Chapter 1: Analysis of marine toxins: gaps on food safety control of marine toxins; Analysis of marine toxins and gaps on food safety control; Gaps on food safety control for marine toxins by chemical methods; Use of standards; New risks in the EU; References; Chapter 2: Pharmacology of ciguatoxins; Chemical structure of ciguatoxins; Voltage-gated sodium channels; Neurological symptoms of ciguatera; Physiological effects of ciguatoxin; Ciguatoxin neurotoxicity; Ciguatoxins, neurological perspectives; References
Chapter 3: Chemistry of pinnatoxinsIntroduction; Isolation; Bioactivity; Detection; Total chemical synthesis; Chemical stability; Conclusions; References; Chapter 4: Chemistry and analysis of PSP toxins; Introduction; Methods of analysis; Chemical methods; References; Chapter 5: Chemistry of palytoxin and its analogues; Introduction; Palytoxin; Palytoxin's analogues from Ostreopsis spp; Ostreocins from O. siamensis; References; Chapter 6: Pharmacology of palytoxins and ostreocins; Introduction; Origin and producing organisms; Toxin distribution and ecological aspects
Pharmacological target of PLTXsPalytoxin toxicology; Detection methods; Future perspectives; References; Chapter 7: Recent insights into anatoxin-a chemical synthesis, biomolecular targets, mechanisms of action and LC-MS detection; Anatoxin-a and analogues; Anatoxins' biomolecular targets and mechanisms of action; LC-MS detection; Conclusions and perspectives; Acknowledgements; References; Chapter 8: Therapeutics of marine toxins; Introduction; Marine toxins as a source of therapeutic compounds; Present marine toxins and derived compound uses
Future of marine toxins and derived compounds usesProblems and advancements in drug discovery from the seas; Conclusions; References; Chapter 9: Marine toxins as modulators of apoptosis; Introduction; Phycotoxins involved in apoptotic processes; Non-apoptotic cytotoxicity of phycotoxins; References; Chapter 10: Cyanobacterial toxins; Introduction; Chemistry of cyanotoxins; Distribution of cyanotoxins; Acknowledgments; References; Chapter 11: Marine toxins and climate change: the case of PSP from cyanobacteria in coastal lagoons; Introduction
Definition of coastal lagoons and main ecosystem characteristicsEcosystem goods and services and human exploitation of coastal lagoons; Eutrophication and climate change in coastal lagoons; Cyanobacteria in coastal lagoons; Paralytic shellfish poisoning and cyanobacteria in coastal lagoons; Conclusions; References; Chapter 12: Microalgae as a source of nutraceuticals; Introduction; Microalgal taxa; World biodiversity of microalgae; Microalgae in culture collections and under commercial cultivation; Commercial use of microalgae as nutraceuticals; Categories of nutraceuticals from microalgae
Summary Dr Luis M Botana is Director of the Community Reference Laboratory for Marine Toxins and Head of the Department of Pharmacology, University of Santiago de Compostela, Spain. Dr Amparo Alfonso is Professor of Pharmacology, University of Santiago de Compostela, Spain
Notes Cholesterol-lowering activity
Print version record
Subject Algal toxins.
Algal toxins
Form Electronic book
Author Alfonso, Amparo
ISBN 9781118500347
1118500342