Title Integrins and ion channels : molecular complexes and signaling / edited by Andrea Becchetti, Annarosa Arcangeli

Published New York : Springer Science+Business Media ; Austin, Tex. : Landes Bioscience, ©2010

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Description 1 online resource (xix, 127 pages) : illustrations Series Advances in experimental medicine and biology ; v. 674 Advances in experimental medicine and biology ; v. 674 Contents Integrin structure and functional relation with ion channels / Annarosa Arcangeli and Andrea Becchetti -- Introduction to ion channels / Chiara Di Resta and Andrea Becchetti -- Biochemical methods to study the interactions between integrins and ion channels / Olivia Crociani -- Optical methods in the study of protein-protein interactions / Alessio Masi [and others] -- Integrins and signal transduction / Sara Cabodi [and others] -- Physical and functional interaction between integrins and HERG1 channels in cancer cells / Serena Pillozzi and Annarosa Arcangeli -- Coordinated regulation of vascular CA2+ and K+ channels by integrin signaling / Peichun Gui [and others] -- Adhesion-dependent modulation of macrophage K+ channels / Margaret Colden-Stanfield -- Integrin receptors and ligand-gated channels / Raffaella Morini and Andrea Becchetti -- Integrins and ion channels in cell migration : implications for neuronal development, wound healing and metastatic spread / Andrea Becchetti and Annarosa Arcangeli Summary Interdisciplinarity is more often invoked than practised. This is hardly surprising, considering the daunting vastness of modern biology. To reach a satisfactory understanding of a complex biological system, a wide spectrum of conceptual and experimental tools must be applied at different levels, from the molecular to the cellular, tissue and organismic. We believe the multifaceted regulatory interplay between integrin receptors and ion channels offers a rich and challenging field for researchers seeking broad biological perspectives. By mediating cell adhesion to the extracellular matrix, int Bibliography Includes bibliographical references and index Notes Print version record Subject Integrins. Ion channels. Cellular signal transduction. Integrins -- metabolism Ion Channels -- metabolism Signal Transduction -- physiology Integrins Ion Channels Signal Transduction SCIENCE -- Life Sciences -- Anatomy & Physiology. Biomédecine. Sciences de la vie. Cellular signal transduction Integrins Ion channels Form Electronic book Author Becchetti, Andrea, 1963- Arcangeli, Annarosa ISBN 9781441960665 144196066X

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