| Description |
1 online resource (866 p.) |
| Contents |
Cover -- Half Title -- Title Page -- Copyright Page -- Table of Contents -- Preface -- Author Biography -- List of Abbreviations -- Chapter 1 Reaction Solvent Selection -- 1.1 Ethereal Solvents -- 1.1.1 Cyclopentyl Methyl Ether -- 1.1.1.1 Brook Rearrangement -- 1.1.1.2 N-Alkylation Reaction -- 1.1.2 Tetrahydrofuran -- 1.1.2.1 Grignard Reagent Formation -- 1.1.2.2 Bromination of Ketone -- 1.1.3 2-Methyl Tetrahydrofuran -- 1.1.3.1 Control of Impurity Formation -- 1.1.3.2 Enhancing Reaction Rate -- 1.1.3.3 Improving Layer Separation -- 1.1.4 Methyl tert-Butyl Ether |
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1.1.4.1 Chlorination Reaction -- 1.1.4.2 Darzens Reaction -- 1.1.5 Diethoxymethane and Dimethoxyethane -- 1.2 Protic Solvents -- 1.2.1 Methanol as a Solvent -- 1.2.1.1 Leak of Palladium Catalyst -- 1.2.1.2 Side Product Formation -- 1.2.1.3 Palladium-Catalyzed Methylation Reaction -- 1.2.2 Ethanol as a Solvent -- 1.2.2.1 Catalytic Reduction of Diaryl Methanol -- 1.2.2.2 SN2 Reaction -- 1.2.3 2-Propanol as a Solvent -- 1.2.3.1 Reaction of Acyl Hydrazine with Trimethylsilyl Isocyanate -- 1.2.3.2 Classical Resolution of Racemic Acid -- 1.2.3.3 Nickel-Catalyzed Addition Reaction -- 1.2.4 1-Pentanol |
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1.2.5 Ethylene Glycol -- 1.3 Water as Reaction Solvent -- 1.3.1 Iodination Reaction -- 1.3.2 Synthesis of Quinazoline-2,4-dione -- 1.3.3 Synthesis of Pyrrolocyclohexanone -- 1.3.4 Synthesis of Thiourea -- 1.3.5 Synthesis of Amide -- 1.3.6 Synthesis of 1,3/1,4-Diketones -- 1.4 Non-Polar Solvents -- 1.4.1 Condensation of Ketone with tert-Butyl Hydrazine Carboxylate -- 1.4.2 Acid-Catalyzed Esterification -- 1.5 Polar Aprotic Solvents -- 1.5.1 Acetone as a Solvent -- 1.5.1.1 Michael Addition Reaction with Acetone Cyanohydrin -- 1.5.1.2 SN2 Alkylation Reaction -- 1.5.1.3 Multi-Component Reactions |
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1.6.5 Hexafluoroisopropanol -- 1.6.5.1 Selective Oxidation of Sulfide -- 1.6.5.2 Cycloaddition Reaction -- 1.7 Carcinogen Solvent -- 1.8 Other Solvents -- 1.8.1 DW-Therm -- 1.8.2 Dowtherm A -- 1.8.2.1 Synthesis of 6-Chlorochromene -- 1.8.2.2 Conrad-Limpach Synthesis of Hydroxyl Naphthyridine -- 1.8.2.3 Conrad-Limpach Synthesis of Quinolone -- 1.8.3 Polyethylene Glycol -- 1.8.4 Propylene Glycol Monomethyl Ether -- 1.8.5 Sulfolane -- 1.8.5.1 Bromination/Esterification -- 1.8.5.2 Fluorine-Exchange Reaction -- 1.8.6 Ionic Liquids -- 1.9 Mixture Of Solvents -- 1.9.1 Aldol Condensation Reaction |
| Summary |
This handbook is designed to provide readers with an unprecedented strategy approach to mechanism-guided process development, helping process chemists and students in industrial chemistry develop chemical processes efficiently. The latest edition addresses common process issues such as safety, cost, robustness, and environmental impact |
| Notes |
Description based upon print version of record |
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1.9.2 Visible-Light Mediated Redox Neutral Reaction |
| Genre/Form |
Electronic books
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| Form |
Electronic book
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| ISBN |
9781000859058 |
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1000859053 |
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