| Description |
1 online resource (294 p.) |
| Contents |
Intro -- Novel Therapeutic Approaches Targeting Oxidative Stress -- Copyright -- Dedication -- Contents -- Contributors -- Preface -- Acknowledgments -- Chapter 1: Novel therapeutic approaches targeting oxidative stress in mood disorders -- 1 Introduction -- 2 The production of ROS in the brain -- 3 The elimination of ROS in the brain -- 4 Oxidative stress in the brain -- 5 Markers of oxidative stress and mood disorders -- 6 Antioxidant treatments in mood disorders -- 6.1 Antioxidant action of conventional treatments for mood disorders |
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6.2 Antioxidants as an add-on therapy in mood disorders -- 6.2.1 N -acetylcysteine (NAC) -- 6.2.2 Medications with some antioxidant action but not as the main mechanism of action -- 6.3 Manipulation of oxidative stress through lifestyle interventions -- 7 Conclusions -- References -- Chapter 2: Ferroptosis: Oxidative stress and pathophysiology -- 1 Introduction -- 2 Immunology -- 3 Conclusion -- Acknowledgment -- Conflict of interest -- References -- Chapter 3: Oxidative stress and its biological significance -- 1 Introduction |
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2 Oxidative stress in 4-hydroxynonenal (HNE) leading to apoptosis -- 3 Antioxidant supplementation increasing tumorigenesis -- 3.1 Generation of mitochondrial ROS and cancer formation -- 4 Regulation of the cell cycle in the oxidative state -- 5 Viral infections and oxidative stress -- 6 Epigenetic factors and carcinogenesis -- 7 Extracellular superoxide angles and apoptosis -- 7.1 HNE and its adducts in the regulation of transcription factors -- 7.2 How oxidative DNA damage is critical to cancer -- 7.3 Transcription factors that promote cancer |
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7.4 Tumor-promoting genetic changes induce endogenous antioxidants -- 7.5 Endogenous antioxidants promote cell migration and metastasis -- 7.6 N -acetylcysteine-More than an antioxidant -- 7.7 The NADPH relationship and the redox potential -- 7.8 The ambiguous relationship between mitochondrial metabolism and ROS -- 7.9 ROS stimulates or inhibits tumorigenesis -- 7.10 Conceptual and experimental limitations of ROS in the field of redox cancer biology -- 7.11 Cell senescence and tumor suppression -- 7.12 The mTOR pathway is involved in the senescent phenotype and cancer |
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8 Extreme oxidative stress with T cells -- 9 Oxidative stress in lung cancer -- 9.1 Adenocarcinoma (AC) -- 9.2 Squamous cell carcinoma (SqCC) -- 9.3 Large cell carcinoma (LCC) -- 10 Inflammation and lung cancer -- 10.1 Risk factors for lung cancer, inflammatory cytokines, and oxidative stress -- 10.2 Immune response T helper 17 (Th17) -- 10.3 Inflammatory cells and lung cancer -- 10.4 Lung cancer and Tregs -- 10.5 Th17 cells and lung cancer -- 10.6 Quantitative relationships between Th17s and Tregs in lung cancer prognosis -- 10.7 DNA methylation and lung cancer |
| Notes |
Description based upon print version of record |
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10.8 ATP and NSCLC-dependent chromatin remodeling complexes SWI/SNF |
| Form |
Electronic book
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| Author |
Qamar, Imteyaz
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| ISBN |
9780323909068 |
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032390906X |
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