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Title The ubiquitin proteasome system in the central nervous system : from physiology to pathology - 2008 update / Mario Di Napoli and Cezary Wojcik, editors
Edition [Updated ed.]
Published New York : Nova Science Publishers, ©2010


Description 1 online resource (xxiii, 552 pages) : illustrations (some color)
Series Biochemistry research trends series
Biochemistry research trends series.
Contents Mechanisms and substrate specificity of desumoylating enzymes / Miklós Békés and Guy S. Salvesen -- Crosstalk between the ubiquitin and sumo pathways / Huaiyu Sun and Tony Hunter -- The roles of the ubiquitin-proteasome system in the control of circadian clocks / Qun He, Chi-Tai Tang, and Yi Liu -- Roles of the ubiquitin proteasome pathway in transcriptional regulation / Thomas G. Gillette -- Role and function of the ubiquitin-proteasome system in neural stem and progenitor cells / Cord Naujokat and Tomo Šaric -- Ubiquitin/proteasome system in mitotic and mitotic-like regulation during brain development and pathology / Jacek Z. Kubiak and Mark A. Smith -- Role of synapse-localized E3 ubiquitin ligase in regulating neural transmission / Ikuko Yao, Hiroshi Ageta, Mitsutoshi Setou -- Regulation of GABAA receptor synaptic expression by the ubiquitin proteasome system / Richard S. Saliba and Stephen J. Moss -- Roles of the ubiquitin proteasome system in the development and function of the neuromuscular junction / Zhonghua Lu, Mary P. Heyer, and Guoping Feng -- The interrelationship between reactive oxygen species (ROS) and proteasome inhibition as inducers of neuronal cell death / Luena Papa and Patricia Rockwell -- The role of the ubiquitin proteasome system in proinflammatory cytokine signaling in the central nervous system / Kyungsun Choi, Jungsul Lee, and Chulhee Choi
Role of immunoproteasomes in ageing and neurodegenerative diseases / Michele Mishto [and others] -- Glia, inflammasomes, and proteasomes in neurodegenerative and autoimmune diseases / Bosede Adenekan and Maria E. Figueiredo-Pereira -- The ubiquitin-proteasome system and the aggresome-autophagy pathway : intersecting mechanisms of misfolded protein clearance in neurodegenerative disease / James A. Olzmann, Lih-Shen Chin, and Lian Li -- Novel functions of parkin / Antoine Duquette and Edward A. Fon -- Validity of targeting the ubiquitin proteasome system in the establishment of new animal models of Parkinson's disease / Anne M. Landau -- The interrelationship between autophagy and the ubiquitin proteasome system in ALS models / Nobutoshi Morimoto and Koji Abe -- The role of the ubiquitin proteasome system in the pathogenesis of Huntington's disease and other polyglutamine disorders / Mathieu Lesort and Gail V.W. Johnson -- The ubiquitin protesome system dysfunction and protein aggregation after brain ischemia / Bingren Hu and Chunli Liu -- Transient cerebral ischemia triggers a dramatic activation of small ubiquitin-like modifier (sumo) conjugation : possible significance / Wei Yang, Huaxin Sheng, and Wulf Paschen -- Ubiquitination, sumoylation, and de-sumoylation of HIF-1 : a key molecule involved in brain development and adaptation to hypoxia in adult brain / Sui Zhang, Jinke Cheng, and Edward T.H. Yeh -- Tuning nodal signaling via the ubiquitin-proteasome system / Yan Xiao and Chenzhong Kuang -- The role of ubiquitin proteasome system and proteasome inhibitors in brain tumors / Jan Styczynski
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Ubiquitin.
Central nervous system -- Physiology
Central nervous system -- Pathophysiology
Central Nervous System -- metabolism
Central Nervous System Diseases -- metabolism
Proteasome Endopeptidase Complex -- physiology
Proteins -- metabolism
Ubiquitin-Protein Ligase Complexes -- physiology
MEDICAL -- Neuroscience.
PSYCHOLOGY -- Neuropsychology.
Central nervous system -- Physiology
Form Electronic book
Author Di Napoli, Mario (Physician)
Wójcik, Cezary, 1968-
ISBN 9781613240458