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Title Toxicant-receptor interactions : modulation of signal transduction and gene expression / editors, Michael S. Denison, William G. Helferich
Published Washington, DC : Taylor & Francis, ©1998

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Description 1 online resource
Series Target organ toxicology series
Target organ toxicology series.
Contents Part Part I: Xenobiotics and Soluble Receptors -- chapter 1 The Ah Receptor Signal Transduction Pathw ay -- chapter 2 The Peroxisome Proliferator-Activated Receptor: An Orphan Receptor in Xenobiotica Response / Martin Gottlicher -- chapter 3 Effects of Xenobiotics on Hormone Receptors / Debie J. Hoivik -- chapter 4 Interactions Between Environmental Xenobiotics and Estrogen Receptor-Mediated Responses / Daniel L. Villeneuve -- part Part II: Xenobiotics and Transcription Factors -- chapter 5 Barbiturate-Inducible Gene Expression / Armand J. Fulco -- chapter 6 Antioxidant-Inducible Detoxifying Enzyme Gene Expression / Anil K. Jaiswal -- chapter 7 Mechanism of Heavy Metal-Inducible Gene Transcription / Fuminori Otsuka -- part Part III: Xenobiotics and Second Messenger Systems -- chapter 8 Modulation of Protein Kinases by Xenobiotics -- chapter 9 Cellular Calcium Regulation and Signaling -- part Part IV: Analysis of Xenobiotic-Inducible Responses -- chapter 10 Approaches for the Identification of Xenobiotic-Inducible Genes / JohnP. VandenHeuvel
Summary Many of the toxic effects elicited by xenobiotics can be explained at the molecular level by their interaction with receptors or by disruption or interference with receptor-mediated signal transduction pathways. This volume describes molecular approaches and reviews of current research. It provides reviews of numerous research areas which are directly related to the analysis of the molecular mechanism by which xenobiotics modulate signal transduction and gene expression
Bibliography Includes bibliographical references and index
Subject Cellular signal transduction.
Genetic regulation.
Molecular toxicology.
Xenobiotics -- Physiological effect.
Toxicology.
Toxicology
Gene Expression Regulation
Molecular Biology
Signal Transduction
Xenobiotics -- pharmacology
toxicology.
SCIENCE -- Life Sciences -- Cytology.
Toxicology
Cellular signal transduction
Genetic regulation
Molecular toxicology
Xenobiotics -- Physiological effect
Xénobiotiques -- Effets physiologiques.
Transduction du signal cellulaire.
Toxicologie moléculaire.
Régulation génétique.
Form Electronic book
Author Denison, Michael S
Helferich, William
LC no. 97049036
ISBN 9781439805923
143980592X