Acknowledgments; Abstract; Contents; Nomenclature; List of Figures; List of Tables; 1. Introduction; 2. Flowsheet simulation of solids ; 3. Novel dynamic flowsheet simulation system; 4. Modeling of fluidized bed spray granulation ; 5. Multiscale treatment of solids processes; 6. Applications of a novel system for fluidized bed granulation ; Conclusion; References; Appendix; List of publications; Curriculum Vitae