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E-book

Title Vaccine adjuvants : methods and protocols / edited by Christopher B. Fox
Published New York, NY : Humana Press : Springer, ©2017

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Description 1 online resource (xii, 372 pages) : illustrations (some color)
Series Methods in molecular biology, 1064-3745 ; 1494
Springer protocols
Springer protocols (Series)
Methods in molecular biology (Clifton, N.J.) ; v. 1494. 1064-3745
Summary This collection seeks to elucidate the practical methods necessary for successful adjuvant development, with a particular focus on the synthesis, formulation, manufacturing, and characterization aspects involved. Beginning with an overview and a case study, the book then delves into in silico design, chemical synthesis, biosynthesis, and/or purification from natural raw materials of specific adjuvant molecules, adjuvant formulation approaches, the analytical characterization of adjuvant formulations and adjuvant-containing vaccines, as well as the biological characterization of vaccine adjuvant activity, including in vitro and in vivo approaches, to measure innate and adaptive immune responses. Written in the highly successful Methods in Molecular Biology format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and authoritative, Vaccine Adjuvants: Methods and Protocols aims to facilitate vaccine adjuvant product development efforts, making them more accessible, manufacturable, and better characterized
Bibliography Includes bibliographical references and index
Subject Vaccines -- Immunology
Vaccines -- immunology
Adjuvants, Immunologic -- therapeutic use
Immunology.
Medical -- Immunology.
Genre/Form Laboratory manuals
Laboratory manuals.
Manuels de laboratoire.
Form Electronic book
Author Fox, Christopher B. (Christopher Bradford), editor
ISBN 9781493964451
1493964453
1493964437
9781493964437