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Title Regenerative engineering of musculoskeletal tissues and interfaces / edited by Syam P. Nukavarapu, Joseph W. Freeman and Cato T. Laurencin
Published Cambridge, UK : Woodhead Publishing, 2015
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Description 1 online resource
Series Woodhead Publishing series in biomaterials ; number 98
Woodhead Publishing series in biomaterials ; no. 98
Contents Front Cover; Related titles; Regenerative Engineering of Musculoskeletal Tissues and Interfaces; Copyright; Dedication; Contents; List of contributors; Woodhead Publishing Series in Biomaterials; Part One -- Basic elements of musculoskeletal tissue engineering; 1 -- Biomaterials and scaffolds for musculoskeletal tissue engineering; 1.1 Introduction; 1.2 Biomaterials; 1.3 Physical property requirements; 1.4 Scaffolds for musculoskeletal tissue engineering; 1.5 Conclusion and future directions; Acknowledgments; References; 2 -- Cells for musculoskeletal tissue engineering; 2.1 Introduction
2.2 Postnatal progenitor cells for musculoskeletal tissue engineering2.3 Prenatal progenitor cells for musculoskeletal tissue engineering; 2.4 Summary; Acknowledgments; References; 3 -- Growth factors for musculoskeletal tissue engineering; 3.1 Introduction; 3.2 Origin and development of musculoskeletal tissues; 3.3 Molecular regulation of musculoskeletal system development; 3.4 Growth factor-based musculoskeletal tissue regeneration; 3.5 Current approaches for spatiotemporal control of growth factors; 3.6 Future directions; Acknowledgments; References
4 -- Mechanical forces in musculoskeletal tissue engineering4.1 Introduction; 4.2 Mechanical forces in guiding differentiation and extracellular matrix production; 4.3 Mechanical stimuli for tissue regeneration; 4.4 Methods of introducing mechanical stimuli; References; Part Two -- Individual musculoskeletaltissues; 5 -- Bone tissue engineering; 5.1 Introduction; 5.2 Traditional concepts in bone tissue engineering; 5.3 Current and new strategies for engineered bone: discussion and examples; 5.4 Bone tissue engineering challenges and a vision for the future
5.5 The development challenges of an engineered bone productAcknowledgments; References; 6 -- Cartilage tissue engineering; 6.1 Introduction; 6.2 Cartilage anatomy, physiology, and injury; 6.3 Current treatment options; 6.4 Tissue engineering considerations; 6.5 Conclusions; References; 7 -- Ligament tissue engineering; 7.1 Introduction; 7.2 Ligament composition and structure; 7.3 Ligament mechanical properties; 7.4 Ligament injuries and their current clinical outcomes; 7.5 Options for surgical ligament replacement; 7.6 Summary; References; 8 -- Tendon tissue engineering; 8.1 Introduction
8.2 Tendon structure and function8.3 Tendon injury and degeneration; 8.4 Tendon healing; 8.5 Current treatment: the traditional approach; 8.6 Tissue engineering approach; 8.7 Scaffolds; 8.8 Materials selection; 8.9 Nanofibers; 8.10 Mechanical stimulation; 8.11 Cells; 8.12 Growth factors; 8.13 Gene therapy; 8.14 Future trends; 8.15 Conclusions; Acknowledgments; References; 9 -- Meniscus tissue engineering; 9.1 Structure, anatomy, and function of the meniscus; 9.2 Meniscus injury and repair; 9.3 Meniscus replacement; 9.4 Conclusions; References; 10 -- Muscle tissue engineering; 10.1 Introduction
Summary Repair and regeneration of musculoskeletal tissues is generating substantial interest within the biomedical community. Consequently, these are the most researched tissues from the regeneration point of view. Regenerative Engineering of Musculoskeletal Tissues and Interfaces presents information on the fundamentals, progress and recent developments related to the repair and regeneration of musculoskeletal tissues and interfaces. This comprehensive review looks at individual tissues as well as tissue interfaces. Early chapters cover various fundamentals of biomaterials and scaffolds, types of c
Notes Includes index
Online resource; title from PDF title page (ScienceDirect, viewed May 7, 2015)
Subject Musculoskeletal System -- anatomy & histology.
Tissue Engineering -- methods.
Musculoskeletal System -- injuries.
Stem Cells -- physiology.
Wounds and Injuries -- therapy.
Regenerative medicine.
Guided Tissue Regeneration -- methods.
Tissue engineering.
Form Electronic book
Author Freeman, Joseph, editor
Laurencin, Cato T., editor
Nukavarapu, Syam P., editor
ISBN 1782423141 (electronic bk.)
9781782423140 (electronic bk.)