Cover; Series preface; Web resources; Acknowledgment; Contents; 1 Introduction to economic evaluations in clinical trials; 2 Designing economic evaluations in clinical trials; 3 Valuing medical service use; 4 Assessing quality-adjusted life years; 5 Analyzing cost; 6 Analyzing censored cost; 7 Comparing cost and effect: point estimates for cost-effectiveness ratios and net monetary benefit; 8 Understanding sampling uncertainty: the concepts; 9 Sampling uncertainty: calculation, sample size and power, and decision criteria; 10 Transferability of the results from trials
Summary
It is increasingly important to examine the relationship between the outcomes of a clinical trial and the costs of the medical therapy under study. This book provides a practical guide to the techniques and issues involved in conducting economic evaluation in ongoing clinical trials, supported with examples
