| Description |
1 online resource (xv, 497 pages) |
| Contents |
Intro -- Foreword -- Preface -- Acknowledgments -- Contents -- Part I: Basic Science of Oncology -- Oncogenesis, What Is New? -- 1 Oncogenesis and Personalized Cancer Treatment -- 2 The Increasing Role of Immunotherapy -- 3 The Importance of Tissue Adequacy in Biomarker/Ancillary Studies Testing -- 3.1 Sequencing -- 3.2 Fluorescent In-Situ Hybridization (FISH) -- 3.3 RNA Gene Expression -- 3.4 Liquid Biopsies -- 4 The Environment, Chemicals, and Cancer -- 5 Microbial Oncogenesis -- References -- Epidemiology of Cancer -- 1 Introduction -- 2 Cancer Incidence and Trend |
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3 Lifetime Risk for Cancers -- 4 Survival Rates for Cancers -- 5 Cancer Mortality and Trend -- 6 Risk Factors for Cancers -- 7 Summary -- References -- Immunemodulation and Cancer -- 1 Introduction -- 2 Tumor Immunity -- 2.1 Tumor Immunity Require CD8+ T Cell Activation -- 2.2 T Cell Activation Require Antigen Presenting Cell -- 3 Antigen Presenting Cells and Cancer -- 3.1 Basic Biology of Dendritic Cells -- 3.2 DC Plays Pivotal Roles in Tumor Immunity -- 3.3 Cross Talk of DC with T Cells and NK Cells -- 4 Regulation DC by TLR Receptors |
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4.1 Basic Biology of Toll-like Receptors (TLRs) -- 4.2 TLRs Play a Pivotal Role in Bringing Innate and Adaptive Immunity -- 4.3 Antitumor Effect of TLR3 -- 4.4 Antitumor Effect of TLR7and TLR8 -- 4.5 Antitumor Effect of TLR9 -- 5 Activation of T Cell Mediated Tumor Immunity by Immune Check Point Inhibition -- 5.1 T Cell Mediated Tumor Immunity Is Regulated by Balance of Stimulatory and Inhibitory Receptors (Immune Checkpoints) -- 5.2 Programmed Cell Death Protein 1 and Programmed Cell Death Protein Ligand 1 (PD-1/PDL1) -- 5.3 CTLA-4 -- 5.4 TIM-3 -- 5.5 LAG-3 |
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6 The Tumor Microenvironment -- 6.1 Regulatory T Cells in the TME -- 6.2 The Infiltration of Tumor Associated Macrophages and Myeloid-Derived Suppressor Cells in the TME -- 7 Summary -- References -- Cancer Targeted Molecular Therapy -- 1 Introduction -- 2 General Strategies for Identifying Cancer Molecular Targets -- 2.1 Conventional Strategies to Identify Specific Tumor Biomarkers -- 2.2 Next-Generation Sequencing (NGS) -- 3 Molecular Targets Associated with Cancer -- 3.1 Targeting ALK Pathway -- 3.2 Targeting BCL-2 Pathways -- 3.3 Targeting BRAF Pathways -- References |
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CAR T-Cell Therapy -- 1 Introduction -- 2 FDA-Approved CAR T-Cell Therapies (Accurate as to the Time of Writing) -- 3 Anti-CD19 CAR T-Cells -- 4 Anti-BCMA CAR T-Cells -- 5 Pre-CAR T Cell Therapy Evaluation and Preparation -- 6 Therapy Process -- 7 Toxicities of CAR T-Cell Therapy -- 8 Common Operative Procedures -- 9 Preoperative Assessment -- 10 Anesthetic Management -- 11 Conclusion -- References -- Part II: Perioperative Oncology -- The Surgeon: Anesthesia Professional Relationship -- 1 Introduction -- 2 Operating Team: Anesthesia Team Dynamics |
| Summary |
This book fills the need for a single comprehensive work on oncological anesthesia written by anesthesiologists. Divided into 14 distinct sections, this title includes the most up-to-date surgical oncologic procedures/treatments (new adjunctive treatments, new surgical techniques), perioperative care and anesthetic considerations and protocols. The highly experienced authors explain how the new treatments affect anesthesia implementations. Chapters are formatted to be "Comprehensive and Concise", COMPREHENSIVE means the book will cover almost everything related to the anesthetic management of oncological surgical procedures and treatment, CONCISE means each chapter will be practical in format to include surgical highlights, positions, paralysis, anesthesia options, monitoring, durations, anesthesia key points, postoperative analgesia, and postoperative destinations. An invaluable resource for anesthesiologists, certified registered nurse anesthetists (CRNA), certified Anesthesiologist assistants (CAA), anesthesia trainees (anesthesiology residents/fellows, students registered nurse anesthetists, student Anesthesiologist assistants), and oncological surgeons |
| Notes |
3 Surgeon: Anesthesia Professional Familiarity |
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Description based on online resource; title from digital title page (viewed on March 19, 2024) |
| Subject |
Cancer -- Surgery.
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| Form |
Electronic book
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| Author |
Huang, Jeffrey, editor
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Huang, Jiapeng, editor
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Liu, Henry, editor
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| ISBN |
9783031509773 |
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3031509773 |
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