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Book Cover
E-book

Title Molecular biology of long non-coding RNAs / Ahmad M. Khalil, Jeff Coller, editors
Published New York : Springer, 2013

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Description 1 online resource (x, 227 pages) : illustrations (some color)
Series 2012-2013 Springer E-Books - Biomedical & Life Sciences
Contents Chromatin Regulation by Long Non-coding RNAs / Daniel C. Factor, Paul J. Tesar -- Regulation of Eukaryotic Cell Differentiation by Long Non-coding RNAs / Juan R. Alvarez-Dominguez, Wenqian Hu -- Roles of Long Non-coding RNAs in X-Chromosome Inactivation / J. Mauro Calabrese, Terry Magnuson -- Roles of Long Non-coding RNAs in Genomic Imprinting / Kristen Martins-Taylor, Stormy J. Chamberlain -- Dysregulation of Long Non-coding RNAs in Human Disease / Nianwei Lin, Tariq M. Rana -- Functions of Long Non-Coding RNAs in Non-mammalian Systems / Alex Tuck, David Tollervey -- Emerging Technologies to Study Long Non-coding RNAs / Fereshteh Jahaniani, Varsha Rao -- Long Non-coding RNAs and Nuclear Body Formation and Function / Ellen Fortini, Ruohan Li, Archa H. Fox
Summary Long non-coding RNAs (lnc)RNAs have emerged as a new paradigm in epigenetic regulation of the genome. Thousands of lncRNAs have been identified and observed in a wide range of organisms. Unlike mRNA, lncRNA have no protein-coding capacity. So, while their function is not entirely clear, they may serve as key organizers of protein complexes that allow for higher order regulatory events. Discovering these functions has been the result of intense research done of the last few years, and lncRNA research has had several critical developments during that time. This book consolidates these ideas and models to better examine the most important issues in lncRNA biology. This includes critical studies that have led to the discovery and annotation of lncRNAs in numerous species, and the molecular mechanisms for a few lncRNA that have begun to emerge
Notes Includes index
Bibliography Includes bibliographical references and index
Notes English
Online resource; title from PDF title page (SpringerLink, viewed September 24, 2013)
Subject Non-coding RNA.
RNA, Untranslated
SCIENCE -- Life Sciences -- Biochemistry.
Non-coding RNA
Form Electronic book
Author Khalil, Ahmad M., editor
Coller, Jeff, editor
ISBN 9781461486213
1461486211
1461486203
9781461486206