| Description |
1 online resource (xviii, 572 pages) : illustrations (some color) |
| Contents |
Chapter 1 Drug design and discovery: an overview -- chapter 2 Role of molecular recognition in drug design -- chapter 3 Stereochemistry in drug design -- chapter 4 Computer-aided development and use of threedimensional pharmacophore models -- chapter 5 Quantitative structure-activity relationships and experimental design -- chapter 6 Receptors: structure, function and pharmacology -- chapter 7 Ion channels: structure, function and pharmacology -- chapter 8 Radiotracers: synthesis and use in imaging -- chapter 9 Excitatory and inhibitory amino acid receptor ligands -- chapter 10 tylcholine and histamine receptors and receptor ligands: medicinal chemistry and therapeutic aspects -- chapter 11 Dopamine and serotonin receptor and transporter ligands -- chapter 12 Enzymes and enzyme inhibitors -- chapter 13 Metals in medicine: inorganic medicinal chemistry -- chapter 14 Design and application of prodrugs -- chapter 15 Peptides and peptidomimetics -- chapter 16 Classical antiviral agents and design of new antiviral agents -- chapter 17 Anticancer agents |
| Summary |
This second edition of ""Textbook of Drug Design"" has been thoroughly revised and updated to provide a complete source of information on all facets of drug design for students of chemistry, pharmacy, pharmacology, biochemistry and medicine.; The book follows drug design from the initial structure-activity relationship to the final processes of clinical evaluation and registration. Chapters investigate the design of drugs for particular cellular targets such as ion channels and receptors whilst others examine specific classes of drug such as peptidomimetics, anti-virals and anti-cancer agents |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Drugs -- Design.
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Drug development.
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Drug Design
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Drug development
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Drugs -- Design
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Arzneimitteldesign
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Arzneimittelentwicklung
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Química farmacêutica.
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Fármacos.
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| Form |
Electronic book
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| Author |
Krogsgaard-Larsen, Povl
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Liljefors, Tommy
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Madsen, Ulf
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| ISBN |
9780203301371 |
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0203301374 |
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9781134457236 |
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1134457235 |
|
9781134457274 |
|
1134457278 |
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9781134457281 |
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1134457286 |
|
