TABLE OF CONTENTS; 1. INTRODUCTION; 2. HISTIDINE-BASED ARTIFICIAL AMINO ACIDS FOR THE MODIFICATION OF METAL BINDING SITES IN BIOMOLECULES; 3. DIFLUORINATED FATTY ACIDS; 4. DEVELOPMENT OF A NEW AUXILIARY-MEDIATED LIGATION STRATEGY; 5. SUMMARY; 6. EXPERIMENTAL PART; ABBREVIATIONS; REFERENCES; ACKNOWLEDGEMENT; CURRICULUM VITAE
