| Description |
1 online resource (560 p.) |
| Contents |
Cover -- Half Title -- Title Page -- Copyright Page -- Table of Contents -- Preface -- Chapter 1: Biomaterial-Based Particulate Drug Carriers -- 1.1: Introduction -- 1.1.1: The Needs for Drug Carriers -- 1.1.2: Drug Carriers: Essential Requirements -- 1.1.3: Major Categories of Drug Carriers -- 1.1.4: Carrier-Mediated Drug Targeting -- 1.2: Biomaterial-Based Particulate Drug Carriers: Advantages and Drawbacks -- 1.2.1: A Wide Choice of Raw Materials -- 1.2.2: Utilizing Nature's Sites for Targeting and High-Affinity Binding |
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1.2.3: Lower Risks of Adverse Effects, Toxicity, and Undesirable Immune Responses -- 1.2.4: Drawbacks of Biomaterial-Based Particulate Drug Carriers -- 1.3: Particle Size, Route of Administration, and Therapeutic Needs -- 1.3.1: The Conceptual Approach and Definitions of Passive and Active Targeting -- 1.3.2: Systemic Administration, Passive and Active Targeting -- 1.3.3: Administration by Local Injection -- 1.3.4: Oral Administration of Drug-Carrier Formulations -- 1.4 Conclusions and Future Prospects -- Chapter 2: Single-Chain Polymer Nanoparticles for Application in Nanomedicine |
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3.1.2: Polymer Characterization of PEO-PCL -- 3.1.3: Characterization of PEO-PCL Micelles -- 3.1.3.1: CMC measurements -- 3.1.3.2: Relative core microviscosity -- 3.2: Drug Delivery from Diblock PEO-PCL Copolymer Micelles -- 3.2.1: Drug Delivery of Anti-Cancer Agents from Diblock PEO-PCL Micelles -- 3.2.2: Flory-Huggins Interaction Parameters Between Drugs and Polymeric Cores -- 3.2.3: Drug Delivery from Triblock Copolymer Micelles of PEO and PCL Blocks -- 3.2.4: Drug Delivery from Star Copolymer Micelles of PEO and PCL -- 3.2.5: Drug Delivery from Substituted Diblock PEO-PCL Copolymer Micelles |
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3.3: Characterization of Cellular Uptake and Pre-Clinical Efficacy in vivo -- 3.3.1: Cellular Internalization of PEO-PCL Micelles -- 3.3.2: Cellular Distribution of PEO-PCL Micelles -- 3.3.3: Efficacy and Stability of PEO-PCL Micelle Drug Delivery in vivo -- 3.3.3.1: Fate of PEO-PCL micelles in vivo -- 3.3.3.2: Stability of PEO-PCL micelles in vivo -- 3.4: Concluding Remarks -- Chapter 4: Recent Progress in Polymer Therapeutics as Nanomedicines -- 4.1: Introduction -- 4.1.1: Polymeric Backbone -- 4.1.1.1: Degradable polymers backbone -- 4.1.1.2: Non-degradable polymer backbone -- 4.1.2: Linker |
| Notes |
Description based upon print version of record |
| Form |
Electronic book
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| ISBN |
9781000284287 |
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100028428X |
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