| Description |
1 online resource (xxx, 587 pages) : color illustrations |
| Contents |
Front Cover -- Colorectal Cancer -- Copyright Page -- Dedication -- Contents -- List of contributors -- Preface -- Acknowledgments -- 1 Colorectal cancer: understanding of disease -- 1.1 Introduction -- 1.2 Understanding of disease: colorectal cancer -- 1.2.1 Etiology and pathogenesis -- 1.2.1.1 Environmental factors correlated to the incidence of colorectal cancer -- 1.2.1.1.1 Dietary fat and meat intake -- 1.2.1.1.2 Vegetables, fruits, and fibers -- 1.2.1.1.3 Smoking Cigarette -- 1.2.1.1.4 Alcohol -- 1.2.1.2 Genes involved in the prognosis and pathogenesis of colorectal cancer |
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1.3 Diagnosis for colorectal cancer -- 1.4 Treatment for colorectal cancer -- 1.4.1 Endoscopic treatment -- 1.4.2 Chemotherapy -- 1.4.3 Radiotherapy -- 1.4.4 Targeted therapies -- 1.5 Recent advances in the therapeutic interventions of colorectal cancer -- 1.6 Conclusion -- Abbreviations -- References -- 2 Impact of the microbiome on colorectal cancer development -- 2.1 Introduction -- 2.2 Gut microbiome and colorectal cancer -- 2.2.1 Induction of inflammation by gut microbiota -- 2.2.2 Dysbiosis and gut microbiota (functional diversity of gut microbiota) |
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2.2.3 Bacterial microbiota and colorectal cancer -- 2.2.4 Viral microbiota and colorectal cancer -- 2.2.5 Fungal microbiota and colorectal cancer -- 2.3 Gut microbiota and its derived metabolites -- 2.4 Host microbiota interactions with genomes and epigenomes -- 2.4.1 Interactions with the genome -- 2.4.1.1 Cell cycle regulation -- 2.4.1.2 DNA damage -- 2.4.1.3 Genomic instability -- 2.4.2 Interactions with the epigenome -- 2.4.2.1 DNA methylation -- 2.4.2.2 miRNAs -- 2.4.2.3 Histone modifications -- 2.5 Linking antibiotic-microbiome: risk and attribution of leaky gut to colorectal cancer |
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2.6 Intestinal stem cells and colorectal cancer -- 2.6.1 Intestinal stem cells and their homeostasis -- 2.6.2 Intestinal stem cells or cancer stem cells markers in colorectal cancer -- 2.6.3 Pathways regulating ISCs/CSCs in colorectal cancer -- 2.7 Prognostic or diagnostic microbiome-associated early diagnosis -- 2.8 Therapeutic impact of the gut microbiome on the efficacy of chemotherapy -- 2.9 Preventive dietary mediators and their protective potential in colorectal cancer -- 2.9.1 Dietary fibers -- 2.9.2 Polyunsaturated fatty acids -- 2.9.3 Polyphenols -- 2.9.4 Probiotics |
| Notes |
Description based upon print version of record |
| Bibliography |
Includes bibliographical references and index |
| Notes |
2.10 Concluding remarks and outlook |
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Description based on online resource; title from digital title page (viewed on May 03, 2024) |
| Subject |
Colon (Anatomy) -- Cancer -- Diagnosis
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Colon (Anatomy) -- Cancer -- Treatment
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Rectum -- Cancer -- Diagnosis
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Rectum -- Cancer -- Treatment
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Colorectal Neoplasms -- diagnosis
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Colorectal Neoplasms -- therapy
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| Form |
Electronic book
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| Author |
Prajapati, Bhupendra, editor.
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Philip, Anil K., editor
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Bhattacharya, Sankha, editor
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| ISBN |
9780443138713 |
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0443138710 |
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