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Title Fundamentals of Medicinal Chemistry and Drug Metabolism / edited by M.O. Faruk Khan & Ashok Philip
Published Sharjah, UAE : Bentham Science Publishers, ©2018

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Description 1 online resource (349 pages)
Series Medicinal Chemistry for Pharmacy Students ; v. 1
Medicinal chemistry for pharmacy students ; v. 1
Contents Intro; Introduction; M.O. Faruk Khan1,* and Ashok Philip2; BRIEF HISTORY AND ROLE OF PHARMACISTS; BRIEF HISTORY OF MEDICINAL CHEMISTRY; DEFINITION OF MEDICINAL CHEMISTRY; MEDICINAL CHEMISTRY IN PHARMACY EDUCATION; An Abridged Medicinal Chemistry Vocabulary [15]; Medicinal Chemistry in Drug Discovery and Development; SCOPE OF THIS BOOK SERIES; CONSENT FOR PUBLICATION; CONFLICT OF INTEREST; ACKNOWLEDGEMENT; REFERENCES; Review of Bioorganic Chemistry; M.O. Faruk Khan1,* and Ashim Malhotra2; AN INTRODUCTION TO ORGANIC FUNCTIONAL GROUPS; Alkanes, Alkenes and Cycloalkanes
Definition and Nomenclature of Alkanes, Alkenes and CycloalkanesPhysicochemical Properties of Alkanes, Alkenes and Cyclic Alkanes; Alkyl Halides; Definition and Nomenclature of Alkyl Halides; Physicochemical Properties of Alkyl Halides; Aromatic Compounds; Definition and Nomenclature of Aromatic Compounds; Physicochemical Properties of Aromatic Compounds; Alcohols and Phenols; Definition and Nomenclature of Alcohols and Phenols; Physicochemical Properties of Alcohols and Phenols; Ethers and Thioethers; Definition and Nomenclature of Ethers; Physicochemical Properties of Ethers
Aldehydes and KetonesDefinition and Nomenclature of Aldehydes and Ketones; Physicochemical Properties of Aldehydes and Ketones; Amines; Definition and Nomenclature of Amines; Physicochemical Properties of Amines; Carboxylic Acids and Derivatives; Definitions and Nomenclatures of Carboxylic Acids and Derivatives; Physicochemical Properties of Carboxylic Acids and Derivatives; Few Pharmaceutically Important Heterocyclic Ring Systems; Five-Membered Unsaturated Heterocycles; Six-Membered Unsaturated Heterocycles; Fused-ring Heterocycles; Tricyclic, Tetracyclic and Bridged Ring Systems
THE BIOMOLECULESCarbohydrates; Classification of Carbohydrates; Other Important Carbohydrates and Derivatives (Fig. 9); Lipids; Fatty Acids; Glycerides (Acylglycerols); Phospholipids; Eicosanoids; Steroids; Proteins; Amino Acids; Isoelectric Point of Amino Acids; Peptides and Proteins; Primary, Secondary, Tertiary and Quaternary Protein Structures (Fig. 22); Nucleic Acids; The Nucleotides and Nucleosides; DNA Structure; DNA Replication; RNA Structure and Transcription; STUDENT SELF-STUDY GUIDE; STUDENTS SELF-ASSESSMENT; CONSENT FOR PUBLICATION; CONFLICT OF INTEREST; ACKNOWLEDGEMENT
Summary The primary objective of this 4-volume book series is to educate PharmD students on the subject of medicinal chemistry. The book set serves as a reference guide to pharmacists on aspects of chemical basis of drug action. This first volume of the series is
Bibliography Includes bibliographical references and index
REFERENCESAcid-base Chemistry and Salt Formation; Hardeep Sing Saluja1 and M.O. Faruk Khan2,*; INTRODUCTION; ACID-BASE THEORIES; Arrhenius Concept; Brønsted-Lowry Concept; Lewis Concept; Application of Lewis and Brønsted-Lowry Definitions to Imidazole; ACIDIC AND BASIC FUNCTIONAL GROUPS OCCUR IN DRUG MOLECULES; Oxy Acids; Thio Acids; Amine Bases; Aromatic Amines; Acidic Amides (Azo Acids) ; ß-Diketone; ACID-BASE STRENGTHS; Acid-Conjugate Base and Base-Conjugate Acid; Percent Ionization; For Weak Acids (HA Acids) ; For Weak Bases (BH+ Acids) ; Electron Withdrawing Effect
Notes Electron Donating Effect
Print version record
Subject Pharmaceutical chemistry.
Drugs -- Metabolism.
Chemistry, Pharmaceutical
MEDICAL -- Pharmacology.
Pharmacy.
MEDICAL.
Drugs -- Metabolism
Pharmaceutical chemistry
Genre/Form Electronic books
Form Electronic book
Author Khan, M. O. Faruk
Philip, Ashok
ISBN 9781681086873
1681086875