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Title Ocular oncology / edited by Daniel M. Albert, Arthur Polans
Published New York : Marcel Decker, [2003]
Online access available from:
ProQuest Ebook Central (owned titles)    View Resource Record  


Description 1 online resource (xiii, 509 pages) : illustrations
Contents 1. Clinical overview of uveal melanoma: introduction to tumors of the eye / J. William Harbour -- 2. Clinical overview: retinoblastoma / Jerry A. Shields and Carol L. Shields -- 3. Epidemiology of uveal melanoma: patient characteristics, risk factors, and predisposing elements / Marie Diener-West and Claudia Scala Moy -- 4. Epidemiology of retinoblastoma / James J. Augsburger -- 5. Genetics of uveal melanoma: chromosomal rearrangements and the identification of genes involved in tumorigenesis / Karen Sisley and Ian G. Rennie -- 6. Structural alterations and gene expression in the pathogenesis of uveal melanoma / Paul R. van Ginkel -- 7. A cascade of genomic changes leads to retinoblastoma / Vivette D. Brown, Helen S.L. Chan, and Brenda L. Gallie -- 8. The role of the retinoblastoma protein in health, malignancy, and the pathogenesis of retinoblastoma / Kurtis R. Van Quill and Joan M. O'Brien -- 9. Biochemical pathways: differential gene expression and cellular pathways determining tumor phenotype comparison of uveal melanocytes and uveal melanoma cells in vitro / Dan-Ning Hu and Steven A. McCormick -- 10. p53 and the molecular regulation of cell fate in retinoblastoma / Robert W. Nickells and Cassandra L. Schlamp -- 11. Immunology of uveal melanoma: adaptive antitumor immunity and the basis of immunotherapy / Jerry Y. Niederkorn -- 13. Models of uveal melanoma: characterization of transgenic mice and other animal models for melanoma / Stefan Dithmar and Hans E. Grossniklaus -- 14. Using retinoblastoma models to develop new treatment: vitamin D analogues / Daniel M. Albert, Robert W. Nickells, Soesiawati R. Darjatmoko, and Isabelle Audo -- 15. Therapy of uveal melanoma: methods and risk factors associated with treatment / Dan S. Gombos and William F. Mieler -- 16. The treatment of retinoblastoma / David H. Abramson and Amy C. Schefler -- 17. Clinical trials in uveal melanoma: patient characteristics and the treatment of intraocular tumors / Timothy G. Murray, H. Culver Boldt, Brandy Hayden, and Claudia Scala Moy -- 18. Clinical trials in retinoblastoma / Emily Y. Chew -- 19. Pathology of uveal melanoma: histological parameters and patient prognosis / Robert Folberg and Jacob Pe'er -- 20. Retinoblastoma: pathology and prognosis / Ian W. McLean -- 21. Molecular genetics of retinoblastoma / Isabelle Audo and José Sahel -- 22. Genetically engineered mouse models of retinoblastoma / Jolene J. Windle and Daniel M. Albert -- 23. Treatment of extraocular retinoblastoma / Diane Puccetti -- Index
Summary This reference deals principally with the molecular biology and genetic factors which trigger and promote the two most common ocular tumours: uveal melanoma and retinoblastoma
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Eye -- Cancer.
Retina -- Cancer.
Uvea -- Cancer.
Angiogenesis Inhibitors -- therapeutic use.
Clinical Trials as Topic.
Eye Neoplasms -- pathology.
Retinal Neoplasms -- pathoogy
Retinoblastoma -- pathology.
Uveal Neoplasms -- pathology.
Form Electronic book
Author Albert, Daniel M.
Polans, Arthur.
ISBN 020391113X
0824756312 (electronic bk.)
9780824756314 (electronic bk.)