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Book Cover
E-book

Title Intracellular delivery : fundamentals and applications / Aleš Prokop, editor
Published Dordrecht ; New York : Springer, ©2011

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Description 1 online resource (xix, 867 pages) : illustrations
Series Fundamental biomedical technologies
Fundamental biomedical technologies.
Contents pt. 1. Mechanisms of uptake and targeting -- pt. 2. Nanocarrier formulation -- pt. 3. Medical applications
Summary This book features a special subsection of Nanomedicine, an application of nanotechnology to achieve breakthroughs in healthcare. It exploits the improved and often novel physical, chemical and biological properties of materials only existent at the nanometer scale. As a consequence of small scale, nanosystems in most cases are efficiently uptaken by cells and appear to act at the intracellular level. Nanotechnology has the potential to improve diagnosis, treatment and follow-up of diseases, and includes targeted drug delivery and regenerative medicine; it creates new tools and methods that impact significantly existing conservative practices. This volume is a collection of authoritative reviews. In the introductory part we define the field (intracellular delivery). Then, we first we cover fundamental routes of nanodelivery devices cellular uptake, types of delivery devices, particularly in terms of localized cellular delivery, both for small drug molecules, macromolecular drugs and genes; all at academic and applied levels. Following is dedicated to enhancing delivery via special targeting motifs. Second, we introduce different types of intracellular nanodelivery devices (their chemistry, although the coverage is far from complete) and ways of producing these different devices. Third, we put special emphasis on particular disease states and on other biomedical applications. Diagnostic and sensing is also included. The intracellular delivery/therapy is a very pregnant topic which will stir great interest. Intracellular delivery enables much more efficient drug delivery since the impact (on different organelles and sites) is intracellular as the drug is not supplied externally within the blood stream. There is a great potential for targeted delivery with improved localized delivery and efficacy
Analysis celbiologie
cellular biology
nanotechnologie
nanotechnology
geneeskunde
medicine
Cellular Biology
Celbiologie
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Drug delivery systems.
Nanomedicine.
Biomedical engineering.
Cytology.
Biomedical Engineering
Cell Biology
Drug Delivery Systems
Nanomedicine
Cytology
biomedical engineering.
Cytology
Biomedical engineering
Drug delivery systems
Nanomedicine
Form Electronic book
Author Prokop, Aleš
ISBN 9789400712485
9400712480
9789400712478
9400712472