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Book Cover
E-book
Author Prokop, Aleš

Title Systems biology in biotech & pharma : a changing paradigm / Aleš Prokop, Seth Michelson
Published Dordrecht ; New York : Springer, ©2012

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Description 1 online resource (xviii, 127 pages)
Series SpringerBriefs in pharmaceutical science & drug development, 1864-8118 ; 2
SpringerBriefs in pharmaceutical science & drug development ; 2
Contents Abstract -- 1 Introduction: Discovery & Development -- New Facet Of Industry, New Tools And Lead Optimization: 1.1 Scope And Content Of This Review -- 2 Discovery: Use Of Systems Biology For Identifying Targets -- 3 Integrative Systems Biology I -- Biochemistry:¡ Phase I Lead Discovery & Molecular Interactions -- 4 Integrative Systems Biology Ii -- Molecular Biology:¡ Phase 2 Lead Discovery & In Silico Screening -- 5. Discovery: Computational Systems Biology (Csb) In Health & And Disease I -- 6 Development:¡ In Vivo Pharmacology -- Systems Biology In Health & Disease Ii -- 7 Development: Pharmacokinetics -- Systems Biology In Health & Disease Iii -- 8 Development:¡ Multiscale Csb -- Simulation Tools -- 9 Development:¡ Drug Formulation & Delivery -- 10 Development: Preclinical Model Based Drug Development -- 11 Systems Biology: Impact On Pharma And Biotech -- 12 Acknowledgment -- 13 Bibliography
Summary Annotation The US is currently well ahead of the rest of the world in the development and application of SB and its principles especially as they pertain to basic medical research and development. This lead is largely due to its earlier start in the academic arena. However, there is evidence of rapid development in both the UK/EU and Japan, and the gap is narrowing, particularly in the UK. From an industrial point of view, the Pharmaceutical Industry based in the US and UK can capitalize on these opportunities and gain the benefits of this technology. Many educational institutions (particularly their medical divisions) at present are heavily business-oriented, realize that in this particular industrial environment, that every dollar counts
Analysis Medicine
Pharmaceutical technology
Biotechnology
Microbiology
Biomedicine general
Applied Microbiology
Pharmaceutical Sciences/Technology
Bibliography Includes bibliographical references
Subject Systems biology.
Bioinformatics.
Biotechnology.
Pharmacology -- Technological innovations
Pharmacology.
Systems Biology
Computational Biology
Biotechnology
Pharmacology
bioengineering.
pharmacology.
NATURE -- Reference.
SCIENCE -- Life Sciences -- Biology.
SCIENCE -- Life Sciences -- General.
Médecine.
Pharmacology
Bioinformatics
Biotechnology
Systems biology
Form Electronic book
Author Michelson, Seth
ISBN 9789400728493
9400728492
9400728484
9789400728486