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Book Cover
E-book
Author Kielhorn, J.

Title 2-butenal / first draft prepared by J. Kielborn and I. Mangelsdorf ; and K. Ziegler-Skylakakis
Published Geneva : World Health Organization, ©2008

Copies

Description 1 online resource (vi, 47 pages) : illustrations
Series Concise international chemical assessment document ; 74
Concise international chemical assessment document ; 74.
Contents COVER; COPYRIGHT; TABLE OF CONTENTS; FOREWORD; 1. EXECUTIVE SUMMARY; 2. IDENTITY AND PHYSICAL/CHEMICAL PROPERTIES; 3. ANALYTICAL METHODS; 4. SOURCES OF HUMAN AND ENVIRONMENTAL EXPOSURE; 5. ENVIRONMENTAL TRANSPORT, DISTRIBUTION, TRANSFORMATION, AND ACCUMULATION; 6. ENVIRONMENTAL LEVELS AND HUMAN EXPOSURE; 7. COMPARATIVE KINETICS AND METABOLISM IN LABORATORY ANIMALS AND HUMANS; 8. EFFECTS ON LABORATORY MAMMALS AND IN VITRO TEST SYSTEMS; 9. EFFECTS ON HUMANS; 10. EFFECTS ON OTHER ORGANISMS IN THE LABORATORY AND FIELD; 11. EFFECTS EVALUATION; 12. PREVIOUS EVALUATIONS BY IOMC BODIES; REFERENCES
Summary 2-Butenal (also known as crotonaldehyde) is an ab-unsaturated aldehyde and consequently a very reactive compound. It is a chemical intermediate used chiefly in the manufacture of sorbates, solvents, and, to a lesser extent, pharmaceutical products and aroma chemicals. This publication studies the pharmacokinetics, environmental exposure, chemical toxicology and carcinogenicity of 2-butenal. However, to enable an understanding and evaluation of this aldehyde in the context of environmental health, other aldehydes, such as formaldehyde, acetaldehyde, and acrolein, are mentioned for comparison.--Publisher's description
Bibliography Includes bibliographical references (pages 32-38)
Notes Summaries in French and Spanish
Print version record
Subject Crotonaldehyde -- Environmental aspects
Crotonaldehyde -- Toxicology
Crotonaldehyde -- Physiological effect
Risk assessment.
Aldehydes -- adverse effects
Aldehydes -- toxicity
Aldehydes -- pharmacokinetics
Environmental Exposure
Inorganic Chemicals -- analysis
Risk Assessment
risk assessment.
HEALTH & FITNESS -- Safety.
Risk assessment.
Crotonaldehyde -- Environmental aspects.
Crotonaldehyde -- Toxicology.
Form Electronic book
Author Mangelsdorf, I.
Ziegler-Skylakakis, K.
World Health Organization
United Nations Environment Programme.
International Labour Organisation
International Program on Chemical Safety
Inter-Organization Programme for the Sound Management of Chemicals.
ISBN 9789240683679
9240683674
1282250019
9781282250017
9786612250019
6612250011
Other Titles Two-butenal