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Title Unraveling the complexities of metastasis : transition from a segmented view to a conceptual continuum / edited by Ammad Ahmad Farooqi, Muhammad Zahid Qureshi, Uteuliyev Yerzhan Sabitaliyevi
Published London, UK : Academic Press, 2022

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Description 1 online resource
Contents 2 -- Multiple roles of circulating tumor cells and exosomes in cancer metastasis: implications for therapeutic inter ... -- Introduction -- CTCs involvement in metastatic progression -- Strategies for isolation and enrichment of CTCs -- Characterization of CTCs -- Exosomes involvement in metastatic progression -- Strategies for detection, isolation, and enrichment of exosomes -- Characterization of exosomes -- Clinical impact of CTCs and exosomes -- Conclusions and future perspectives -- References
3 -- Diagnosis and treatment of metastatic prostate cancer: the role of imaging, liquid biopsies, and biomarkers for ... -- Introduction -- Overview of prostate cancer disease states and treatment options -- Proliferative inflammatory atrophy -- Localized prostate cancer and treatment options -- Metastatic castration-resistant prostate cancer and treatment options -- Improved imaging and image-guided biopsy for prostate cancer -- Imaging signatures of hypoxia -- Gene signature panels for prostate cancer risk stratification
Next-generation sequencing and prostate cancer: cell-free nucleic acids and circulating tumor cells -- Conclusion -- Acknowledgments -- References -- 4 -- Prognostic and predictive role of bone metastasis in NSCLC: risk factors and clinical implications -- Introduction -- Incidence of BMs in NSCLC patients -- Prognostic role -- Localization of BMs -- Histology and driver mutations -- Development of complications and performance status -- Treatments -- Predictive role -- Risk factors for bone metastasis -- Prognostic factors and predictive factors for bone progression
Predictive factors for SRE development -- Clinical implication and treatment -- Conclusion -- References -- 5 -- Brain metastases in breast cancer -- Introduction -- The basis of breast cancer brain metastasis -- The metastatic cascade -- Brain microenvironment and BC -- Neuroinflammation role in metastasis -- Signaling pathways involved in BM from BC -- Differences between the primary tumor cells and BM -- Risk factors for brain metastasis in breast cancer -- Diagnosis -- Treatment -- Prognosis -- Specific conditions -- Brain metastasis from breast cancer in BRCA mutation carriers
Notes Includes index
Print version record
Subject Metastasis.
Neoplasm Metastasis
Metastasis
Form Electronic book
Author Farooqi, Ammad Ahmad
Zhaid Qureshi, Muhammad
Sabitaliyevi, Uteuliyev Yerzhan
ISBN 9780128217900
0128217901