| Description |
xii, 367 pages : illustrations ; 24 cm |
| Series |
Princeton studies in complexity |
|
Princeton studies in complexity.
|
| Contents |
1. Introduction -- Pt. I. Robustness below the gene level -- 2. The genetic alphabet -- 3. The genetic code -- 4. RNA structure -- 5. Proteins and point mutations -- 6. Proteins and recombination -- Pt. II. Robustness above the gene level -- 7. Regulatory DNA regions and their reorganization in evolution -- 8. Metabolic pathways -- 9. Metabolic networks -- 10. Drosophila segmentation and other gene regulatory networks -- 11. Phenotypic traits, cryptic variation, and human diseases -- 12. The many ways of building the same body -- Pt. III. Common principles -- 13. Neutral spaces -- 14. Evolvability and neutral mutations -- 15. Redundancy of parts or distributed robustness? -- 16. Robustness as an evolved adaptation to mutations -- 17. Robustness as an evolved adaptation to environmental change and noise -- 18. Robustness and fragility : advantages to variation and trade-offs -- Pt. IV. Robustness beyond the organism -- 19. Robustness in natural systems and self-organization |
|
20. Robustness in man-made systems -- Epilogue : seven open questions for systems biology |
| Bibliography |
Includes bibliographical references (pages [323]-358) and index |
| Subject |
Mutation (Biology)
|
|
Biological systems -- Stability.
|
|
Robust control.
|
|
Molecular evolution.
|
| LC no. |
2004054936 |
| ISBN |
0691122407 cloth alkaline paper |
|
