| Description |
xiv, 490 pages : illustrations (chiefly color) ; 28 cm |
| Contents |
1. Molecular biotechnology / Wiel P.M. Hoekstra and Sjef C.M. Smeekens -- 2. Biophysical and biochemical analysis of recombinant proteins / Tsutomu Arakawa and John S. Philo -- 3. Production and downstream processing of biotech compounds / Farida Kadir, Mic Hamers, and Paul Ives -- 4. Formulation of biotech products, including biopharmaceutical considerations / Daan J.A. Crommelin -- 5. Pharmacokinetics and pharmacodynamics of peptide and protein drugs / Bernd Meibohm and Rene Braekman -- 6. Immunogenicity of therapeutic proteins / Huub Schellekens and Wim Jiskoot -- 7. Genomics, other "omics" technologies, personalized medicine, and additional biotechnology-related techniques / Robert D. Sindelar -- 8. Gene therapy / Maria A. Croyle -- 9. Oligonucleotides / Raymond M. Schiffelers and Enrico Mastrobattista -- 10. Hematopoietic growth factors / MaryAnn Foote -- 11. Interferons and interleukins / Jean-Charles Ryff, Ronald W. Bordens, and Sydney Pestka -- |
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12. Insulin / John M. Beals, Michael R. DeFelippis, and Paul M. Kovach -- 13. Growth hormones / Melinda Marian and James Q. Oeswein -- 14. Recombinant coagulation factors and thrombolytic agents / Nishit B. Modi -- 15. Monoclonal antibodies : from structure to therapeutic application / Banmeet Anand ... [et al.] -- 16. Monoclonal antibodies in cancer / John C. Kuth ... [et al.] -- 17. Monoclonal antibodies in solid organ transplantation / Nicole Weimert and Rita R. Alloway -- 18. Monoclonal antibodies in anti-inflammatory therapy / Jeffrey M. Harris, Peter Kuebler, and Michael A. Panzara -- 19. Recombinant human deoxyribonuclease I / Robert A. Lazarus and Jeffrey S. Wagener -- 20. Follicle-stimulating hormone / Tom Sam -- 21. Vaccines / Wim Jiskoot, Gideon F.A. Kersten, and Enrico Mastrobattista -- 22. Dispensing biotechnology products : handling, professional education, and product information / Peggy Piascik -- 23. Economic considerations in medical biotechnology / Eugene M. Kolassa -- 24. Regulatory issues and drug product approval for biopharmaceuticals / Vinod P. Shah and Daan J.A. Crommelin |
| Summary |
"Completely revised to reflect significant trends and cutting-edge advances in pharmaceutical biotechnology, including specific therapeutic agents and their applications, this Third Edition provides a well-balanced framework for understanding every major aspect of pharmaceutical biotechnology, including drug development, production, dosage forms, administration, and therapeutic developments. New chapters cover oligonucleotides and siRNA, regulatory issues and drug product approval for biopharmaceuticals, immunogenicity, gene therapy, and various monoclonal antibodies grouped by therapeutic area. Self-assessment questions have also been added to each chapter to reinforce understanding of practical pharmaceutical applications, making this an indispensable volume for classroom use as well as for professional reference in practice or industry." -- Publisher description |
| Notes |
Previous ed. : Pharmaceutical biotechnology : an introduction for pharmacists and pharmaceutical scientists. 2002 |
| Bibliography |
Includes bibliographical references and index |
| Subject |
Pharmaceutical biotechnology.
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Technology, Pharmaceutical.
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| Author |
Crommelin, D. J. A. (Daan J. A.)
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Meibohm, Bernd.
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Sindelar, Robert D.
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| LC no. |
2007025743 |
| ISBN |
1420044370 |
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1420067524 (hb : alk. paper) |
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9781420044379 |
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9781420067521 (hb : alk. paper) |
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