| Description |
xiii, 288 pages : illustrations ; 25 cm |
| Contents |
1.Introduction to Model Systems in Drug Discovery -- 2.Growing Yeast for Fun and Profit: Use of Saccharomyces cerevisiae as a Model System in Drug Discovery -- 3.Caenorhabditis elegans Functional Genomics in Drug Discovery: Expanding Paradigms -- 4.Drosophila as a Tool for Drug Discovery -- 5.Drosophila -- a Model System for Targets and Lead Identification in Cancer and Metabolic Disorders -- 6.Mechanism of Action in Model Organisms: Interfacing Chemistry, Genetics and Genomics |
| Summary |
Fruit flies are "little people with wings" goes the saying in the scientific community, ever since the completion of the Human Genome Project and its revelations about the similarity amongst the genomes of different organisms. It is humbling that most signalling pathways which "define" humans are conserved in Drosophila, the common fruit fly. |
| Bibliography |
Includes bibliographical references and index |
| Subject |
Drugs -- Research.
|
|
Pharmacogenomics.
|
|
Pharmacogenetics -- Animal models.
|
| Author |
Carroll, Pamela M.
|
|
FitzGerald, Kevin J., 1967-
|
| LC no. |
2003013114 |
| ISBN |
0470848936 : |
|
