| Description |
xxii, 752 pages : illustrations (some color), plans ; 27 cm |
| Contents |
Contents note continued: 17.Computers in medicinal chemistry -- 18.Quantitative structure-activity relationships (QSAR) -- Case study 5 Design of a thymidylate synthase inhibitor -- Case study 6 Design of a serotonin antagonist as a possible anxiolytic agent -- Pt. E Selected topics in medicinal chemistry -- 19.Antibacterial agents -- 20.Antiviral agents -- 21.Anticancer agents -- 22.Cholinergics, anticholinergics, and anticholinesterases -- 23.Drugs acting on the adrenergic nervous system -- 24.Opioid analgesics -- 25.Antiulcer agents -- Case study 7 Current research into antidepressant agents -- App. 1 Essential amino acids -- App. 2 The standard genetic code -- App. 3 Statistical data for QSAR -- App. 4 The action of nerves -- App. 5 Microorganisms -- App. 6 Drugs and their trade names |
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Machine generated contents note: 1.Drugs and drug targets: an overview -- Pt. A Drug targets -- 2.Proteins: structure and function -- 3.Enzymes: structure and function -- 4.Receptors: structure and function -- 5.Receptors and signal transduction -- 6.Nucleic acids: structure and function -- Pt. B Pharmacodynamics and pharmacokinetics -- 7.Enzymes as drug targets -- 8.Receptors as drug targets -- 9.Nucleic acids as drug targets -- 10.Miscellaneous drug targets -- 11.Pharmacokinetics and related topics -- Case study 1 Statins -- Pt. C Drug discovery, design, and development -- 12.Drug discovery: finding a lead -- 13.Drug design: optimizing target interactions -- 14.Drug design: optimizing access to the target -- 15.Getting the drug to market -- Case study 2 The design of ACE inhibitors -- Case study 3 Artemisinin and related antimalarial drugs -- Case study 4 The design of oxamniquine -- Pt. D Tools of the trade -- 16.Combinatorial and parallel synthesis -- |
| Notes |
Previous ed.: 2005 |
| Bibliography |
Includes bibliographical references (pages [725]-726) and index |
| Subject |
Pharmaceutical chemistry.
|
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Pharmacokinetics.
|
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Chemistry, Pharmaceutical.
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Drug Design.
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Pharmacokinetics.
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| Author |
Spencer, John, 1968-
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| LC no. |
2009417121 |
| ISBN |
0199234477 (paperback) |
|
9780199234479 (paperback) |
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