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Title Acute promyelocytic leukemia : molecular genetics, mouse models and targeted therapy / P.P. Pandolfi and P.K. Vogt (eds.)
Published Berlin ; New York : Springer, ©2007


Description 1 online resource (vi, 273 pages) : illustrations
Series Current topics in microbiology and immunology, 0070-217X ; 313
Current topics in microbiology and immunology ; 313. 0070-217X
Contents APL as a paradigm in biomedical research : a journey toward the cure / P.P. Pandolfi -- Mouse models of acute promyelocytic leukemia / S.C. Kogan -- The PLZF gene of t(11;17)-associated APL / M.J. McConnell and J.D. Licht -- SUMO, the three Rs and cancer / J.-S. Seeler [and others] -- Emerging role for microRNAs in acute promyelocytic leukemia / C. Nervi [and others] -- The theory of APL revisited / P.P. Scaglioni and P.P. Pandolfi -- Treatment of acute promyelocytic leukemia by retinoids / P. Fenaux, Z.Z. Wang, and L. Degos -- Arsenic trioxide and acute promyelocytic leukemia : clinical and biological / Z. Chen [and others] -- Front line clinical trials and minimal residual disease monitoring in acute promyelocytic leukemia / F. Lo-Coco and E. Ammatuna -- Histone deacetylase inhibitors in APL and beyond / K. Petrie, N. Prodomou, and A. Zelent -- Monoclonal antibody therapy of APL / P.G. Maslak, J.G. Jurcic, and D.A. Scheinberg -- Targeting APL fusion proteins by peptide interference / A. Melnick -- The design of selective and non-selective combination therapy for acute promyelocytic leukemia / Y. Jing and S. Waxman
Summary "This volume is meant to summarize some of the most recent progress made in elucidating the pathogenesis of Acute Promyelocytic Leukemia (APL) and in the treatment of this form of leukemia. It is also meant to celebrate one of the most successful accomplishments in cancer research and contemporary biomedical research."--Jacket
Bibliography Includes bibliographical references and index
Notes Print version record
In Springer e-books
Subject Acute myeloid leukemia -- Pathogenesis
Acute myeloid leukemia -- Treatment
Leukemia, Promyelocytic, Acute -- drug therapy
Antineoplastic Agents -- therapeutic use
MEDICAL -- Oncology.
HEALTH & FITNESS -- Diseases -- Cancer.
Antineoplastic Agents -- therapeutic use.
Acute myeloid leukemia -- Pathogenesis.
Acute myeloid leukemia -- Treatment.
Leukemia, Promyelocytic, Acute -- drug therapy.
Sciences de la vie.
Form Electronic book
Author Pandolfi, P. P. (Pier Paolo)
Vogt, P. K. (Peter K.), 1932-
ISBN 9783540345947