1. End Group Analysis of Proteins. Reactions of the Amino Group. Reactions of the Carboxyl Group -- 2. Limited Hydrolysis of Proteins. Cyanogen Bromide. Trypsin. Chymotrypsin. Elastase. Pepsin -- 3. Base Sequencing of DNA. The Maxam-Gilbert Method. The Sanger Method -- 4. Analysis of DNA by Restriction Mapping. Single Enzyme Digests. Multiple Enzyme Digests -- 5. Additional Problems -- 6. Adventures in Sequencing. Biocryptography -- A New Science. A Night at the Opera (House). From Baltimore with Love. Summertime, and Is the Living Easy?