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Title L-arginine in clinical nutrition / Vinood B. Patel, Victor R. Preedy, Rajkumar Rajendram, editors
Published Switzerland : Humana Press, [2016]


Description 1 online resource (xxx, 645 pages) : illustrations (some color)
Series Nutrition and health
Nutrition and health (Totowa, N.J.)
Contents Preface; Series Editor Page; Part I: Basic Processes at the Cellular Level; Part II: l-Arginine Metabolism and Functions; Part III: l-Arginine Status in Cells Related to Organ Damage and Disease; Part IV: l-Arginine Status and Use in Healthy Individuals; Part V: l-Arginine and Diseases of the Gastrointestinal Tract (GI Tract); Part VI: Therapeutic Uses of l-Arginine: Diabetes, Obesity, and Cardiovascular Diseases; Part VII: Therapeutic Uses of l-Arginine: Cancer, Sickle Cell Disease, Wound Healing, and Infectious Disease; About the Series Editor; Editor Biography; Contents; Contents
Part I: Basic Processes at the Cellular LevelsChapter 1: l-Arginine Uptake by Cells; Introduction; Cationic Amino Acid Transport; Measurement of l-Arginine Uptake; Non-linear Modelling of Uptake; Validation of a Non-linear Method Determining l-Arginine Uptake; Effect of Salt and Inhibitors on l-Arginine Uptake; Kinetics of l-Arginine Transport and the l-Arginine Paradox; Conclusions; References; Chapter 2: l-Arginine and the Expression of HSP70 and p53 Proteins; Introduction; Heat Shock Proteins; Programmed Cell Death, p53 and Caspase 3; Previous Studies on l-Arginine
ConclusionsReferences; Chapter 3: AMP-Activated Protein Kinase and l-Arginine; Introduction; Intracellular ARG Does Not Determine NO Production; Dualistic Nature of NOS; Role of Oxidative Stress During ARG Continuous Supplementation; Role of NOS Cofactor (BH4) in Tolerance; Role of AMP-Activated Protein Kinase (AMPK) Towards ARG Responses; Conclusion; References; Chapter 4: Amidine-Based Compounds Affecting l-Arginine Metabolism; Introduction; Amidine-Based Inhibitors of Nitric Oxide Synthase; Amidine-Based Inhibitors of Human DDAH1; Amidine-Based Inhibitors of PAD
L-Arginine-Based Inhibitors of PRMT1 Conclusions; References; Chapter 5: Oxy- and Sulfoanalogues of l-Arginine; Introduction; Biological Role of Canavanine, a Natural Oxy-l-arginine Analogue; Synthesis and Biological Effects of Synthetic Oxy- and Sulfoarginine Analogues; Conclusion; References; Chapter 6: Regulation of Expression and Activity of l-Arginine Transporters by Nutrients and Hormones: A Focus in Transcriptional Mechanisms Regulated by Glucose and Insulin; Introduction; l-Arginine Transporters and Endothelial Function; Transcriptional Regulation of CAT-1
Regulation of SLC7A1 by Insulin Regulation of SLC7A1 by d-glucose; Conclusions; References; Chapter 7: l-Arginine, Pancreatic Beta Cell Function, and Diabetes: Mechanisms of Stimulated Insulin Release and Pathways of Metabolism; Introduction; Molecular Mechanisms of l-Arginine-Induced Insulin Release; A Potential Role for PEDF in Modulating Beta Cell l-Arginine and Lipid Metabolism: Impact on Insulin Secretion; l-Arginine Supplementation in Sport, Exercise, and Diabetes; Conclusion; References; Chapter 8: Erythrocytes By-Products of l-Arginine Catabolism; Introduction
Summary This text presents the application of current nutritional knowledge by physicians and incorporates emerging fields of science and important discoveries. Written by authors of international and national standing, leaders in the field and trendsetters, Arginine in Clinical Nutrition is essential reading for nutritionists and dietitians, public health scientists, doctors, epidemiologists, health care professionals of various disciplines, policy makers and marketing and economic strategists
Notes Includes index
Online resource; title from PDF title page (EBSCO, viewed September 19, 2016)
Subject Arginine.
Amino acids in human nutrition.
Dietetics & nutrition.
MEDICAL -- Physiology.
SCIENCE -- Life Sciences -- Human Anatomy & Physiology.
Amino acids in human nutrition.
Form Electronic book
Author Patel, Vinood B., editor
Preedy, Victor R., editor.
Rajenm, Rajkumar, editor
ISBN 9783319260099