Limit search to available items
Book Cover

Title Aminoacyl-tRNA synthetases in biology and medicine / Sunghoon Kim, editor ; with contributions by T.J. Bullwinkle ... [and more]
Published Dordrecht : Springer, 2014


Description 1 online resource (x, 350 pages)
Series Topics in Current Chemistry, 0340-1022 ; 344
Topics in current chemistry ; 344. 0340-1022
Contents Catalysis -- Emergence and Evolution -- Architecture -- Protein-protein Interactions and Multicomponent Complexes -- Interactions with RNAs -- Secretion and Circulation -- Regulatory Roles -- Neural Diseases -- Cancer -- Immune Diseases -- Pathologic Implications of Mitochondrial tRNA Synthetases -- Infectious Diseases -- Reprogramming of Genetic Code -- Novel functions of tRNAs -- Perspectives for Systems and Synthetic Bio-Medicine
Summary 1 Synthetic and Editing Mechanisms of Aminoacyl-tRNA Synthetases John J. Perona, Ita Gruic-Sovulj 2 Emergence and Evolution Tammy J. Bullwinkle, Michael Ibba 3 Architecture and Metamorphosis Min Guo, Xiang-Lei Yang 4 Protein-Protein Interactions and Multi-component Complexes of Aminoacyl-tRNA Synthetases Jong Hyun Kim, Jung Min Han, Sunghoon Kim 5 Extracellular Activities of Aminoacyl-tRNA Synthetases: New Mediators for Cell-Cell Communication Sung Hwa Son, Min Chul Park, and Sunghoon Kim 6. Non-catalytic Regulation of Gene Expression by Aminoacyl-tRNA Synthetases Peng Yao, Kiran Poruri, Susan A. Martinis, Paul L. Fox 7 Amino-Acyl tRNA Synthetases Generate Dinucleotide Polyphosphates as Second Messengers: Functional Implications Sagi Tshori, Ehud Razin, Hovav Nechushtan 8 Association of Aminoacyl-tRNA Synthetases with Cancer Doyeun Kim, Nam Hoon Kwon, Sunghoon Kim 9 Pathogenic Implications of Human Mitochondrial Aminoacyl-tRNA Synthetases Hagen Schwenzer, Joffrey Zoll, Catherine Florentz, Marie Sissler 10 Role of Aminoacyl-tRNA Synthetases in Infectious Diseases and Targets for Therapeutic Development Varun Dewan, John Reader, Karin-Musier Forsyth 11 Flexizymes, Their Evolutionary History and Diverse Utilities Toby Passioura, Hiroaki Suga
Notes Includes index
Online resource; title from PDF title page (SpringerLink, viewed May 13, 2014)
Subject Aminoacyl-tRNA synthetases.
Science des matériaux.
Aminoacyl-tRNA synthetases.
Form Electronic book
Author Kim, Sunghoon, 1972- editor.
Bullwinkle, T. J. (Tammy J.), author.
ISBN 9789401787017