| Description |
1 online resource (xv, 409 pages) : illustrations |
| Series |
Subcellular biochemistry, 0306-0225 ; v. 38 |
|
Sub-cellular biochemistry ; v. 38.
|
| Contents |
The Contribution of Microscopy to the Study of Alzheimer's Disease, Amyloid Plaques and A? Fibrillogenesis -- Transgenic Mouse Models for APP Processing and Alzheimer's Disease: Early and Late Defects -- Oxidative stress in Alzheimer's Disease: Implications for Prevention and Therapy --?-Secretase, APP and A? in Alzheimer's Disease -- The Non-Amyloidogenic Pathway: Structure and Function of?-Secretases -- Amyloid? Degradation: A Challenging Task for Brain Peptidases -- The Protective Role of Vitamin E in Vascular Amyloid?-Mediated Damage -- Amyloid Accumulation and Pathogensis of Alzheimer's Disease: Significance of Monomeric, Oligomeric and Fibrillar A? -- Cholesterol and Amyloid? Fibrillogenesis -- Alzheimer's?-Amyloid: Insights into Fibril Formation and Structure from Congo Red Binding -- The Aluminium-Amyloid Cascade Hypothesis and Alzheimer's Disease -- Amyloid-? Metal Interaction and Metal Chelation -- The Interaction of Amyloid-? with ApoE -- Clusterin and Alzheimer's Disease -- Acetylcholinesterase Interaction with Alzheimer Amyloid? -- Membrane Disordering Effects of?-Amyloid Peptides -- The Role of Alzheimer A? Peptides in Ion Transport Across Cell Membranes -- Amyloid Inhibitors and?-Sheet Breakers -- Cholesterol and Alzheimer's Disease: Statins, Cholesterol Depletion in APP Processing and A? Generation -- Phosphorylated Amyloid-?: the Toxic Intermediate in Alzheimer's Disease Neurodegeneration |
| Summary |
"The volume contains a broad range of current information on cellular, biochemical, and structural aspects of amyloid-[beta], of direct relevance to Alzheimer's disease."--Jacket |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| In |
Springer e-books |
| Subject |
Alzheimer's disease.
|
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Amyloid beta-protein.
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Alzheimer Disease
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Amyloid beta-Peptides
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HEALTH & FITNESS -- Diseases -- Alzheimer's & Dementia.
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MEDICAL -- Neurology.
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Biomédecine.
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Sciences de la vie.
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Alzheimer's disease
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Amyloid beta-protein
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| Form |
Electronic book
|
| Author |
Harris, J. Robin (James Robin)
|
|
Fahrenholz, F. (Falk)
|
| LC no. |
2006530806 |
| ISBN |
9780387232263 |
|
0387232265 |
|
0387232257 |
|
9780387232256 |
|
6610700834 |
|
9786610700837 |
|
