Amyotrophic lateral sclerosis -- Chemotherapy : Spectrums of amyotrophic lateral sclerosis : heterogeneity, pathology, and therapeutic directions / edited by Christopher A. Shaw and Jessica R. Morrice
Amyotrophic Lateral Sclerosis -- drug therapy : Spectrums of amyotrophic lateral sclerosis : heterogeneity, pathology, and therapeutic directions / edited by Christopher A. Shaw and Jessica R. Morrice
Amyotrophic lateral sclerosis -- Genetic aspects : Spectrums of amyotrophic lateral sclerosis : heterogeneity, pathology, and therapeutic directions / edited by Christopher A. Shaw and Jessica R. Morrice
2021
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Amyotrophic Lateral Sclerosis -- genetics : Spectrums of amyotrophic lateral sclerosis : heterogeneity, pathology, and therapeutic directions / edited by Christopher A. Shaw and Jessica R. Morrice
A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
Amyotrophic lateral sclerosis -- Patients -- Ireland -- Biography : It's not yet dark / [FilmRise] ; Newgrange Pictures [and Kennedy Films] presents ; [in association with Bord Scannán na hÉireann / the Irish Film Board ; in association with TV3 and [3 others]] ; produced by Lesley McKimm and Kathryn Kennedy ; directed by Frankie Fenton
A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)