An antiphospholipid antibody found in association with systemic lupus erythematosus (LUPUS ERYTHEMATOSUS, SYSTEMIC;), ANTIPHOSPHOLIPID SYNDROME; and in a variety of other diseases as well as in healthy individuals. In vitro, the antibody interferes with the conversion of prothrombin to thrombin and prolongs the partial thromboplastin time. In vivo, it exerts a procoagulant effect resulting in thrombosis mainly in the larger veins and arteries. It further causes obstetrical complications, including fetal death and spontaneous abortion, as well as a variety of hematologic and neurologic complications
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Anticoagulantia. : Anticoagulants, antiplatelets, and thrombolytics / edited by Shaker A. Mousa
Anticoagulants (Medicina) : Direct oral anticoagulants : from pharmacology to clinical practice / Riccardo Proietti, Ahmed AlTurki, Nicola Ferri, Vincenzo Russo, T. Jared Bunch, editors
Anticonvulsants -- Dictionaries : Epilepsy A to Z : a concise encyclopedia / William O. Tatum IV, Peter W. Kaplan, Pierre Jallon
2009
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Anticonvulsants -- economics. : Economic evaluation of epilepsy management : proceedings of the Symposium on Economic Aspects of Epilepsy at the 21st International Epilepsy Congress in Sydney, 5 September 1995 / edited by Christoph Pachlatko, Roy G. Beran