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Title Application of apoptosis to cancer treatment / [edited] by Mels Sluyser
Published Dordrecht : Springer, ©2005

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Description 1 online resource (vi, 370 pages) : illustrations
Contents Disfunction of the Apoptotic Pathway in Cancer Cells -- Calcium Signaling and Apoptosis Resistance of Cancer Cells -- Cell Clearance and Cancer -- Specific, Pro-Poptotic Cell-Signaling: Design of Novel, Recombinant Targeted Antitumor Agents Operating Exclusively Through Modulation of Cellular Apoptotic Events -- Targeting Oncogenes Which Regulate Apoptosis -- Targeting Cyclins to Cause Cancer Cell Apoptosis -- Apoptosis Induction By Tumor- Targeted Toxins -- Targeting Cell-Death Pathways in Multiple Myeloma: Therapeutic Implications -- Cephalostatin 1-Induced Apoptosis in Tumor Cells -- Hamlet; A Novel Tool to Identify Apoptotic Pathways in Tumor Cells -- Cancer Immunotherapy: On the Trail of a Cure? -- Histone Deacetylase Inhibitors as a Treatment of Trail-Resistant Cancers -- Basis of Cell Kill Following Clinical Radiotherapy -- Imaging of Apoptotic Cells in vivo -- Apoptosis-Inducing Anticancer Drugs in Clinical Trials
Summary "Novel drugs are being developed which interact with the programmed cell death (apoptotic) machinery in cancer cells, thereby causing these cells to commit suicide and to be removed from the body. Research is also directed to investigate why cancer cells sometimes lose the ability to undergo apoptosis after a certain period of time and methods are being developed to reactivate this cell death process." "This book is intended for workers in the field and clinicians as a useful guide of the state of affairs in this field which may offer more effective possibilities for treatment of cancer patients."--Jacket
Bibliography Includes bibliographical references and index
Notes English
In Springer e-books
Subject Cancer -- Treatment.
Apoptosis.
Antineoplastic Agents -- therapeutic use
Apoptosis -- drug effects
Neoplasms -- drug therapy
Apoptosis
MEDICAL -- Oncology.
HEALTH & FITNESS -- Diseases -- Cancer.
Cancer -- Treatment.
Apoptosis.
Biomédecine.
Sciences de la vie.
Apoptosis
Cancer -- Treatment
Genre/Form Electronic books
Form Electronic book
Author Sluyser, M. (Mels), 1930-
ISBN 1402033036
1402033028
9781402033032
9781402033025
1281102954
9781281102959