| Description |
1 online resource (xvi, 407 pages) : color illustrations |
| Contents |
Preface -- Thymocyte development -- A review of mathematical models for T cell receptor triggering and antigen discrimination -- Dynamic tuning of T cell receptor specificity by co-receptors and costimulation -- T cell activation and function: role of signal strength -- The cyton model for lymphocyte proliferation and differentiation -- Modeling itravital two-photon data of lymphocyte migration and interaction -- Modeling lymphocyte dynamics in vivo -- Continuous-time birth and death processes: diversity maintenance of naïve T cells in the periphery -- Multivariate competition processes: a model for two competing T cell clonotypes -- Stochastic modeling of T Cell homeostasis for two competing clonotypes via the master equation -- Dendritic cell migration in the intestinal tract -- Reassessing germinal center reaction concepts -- B cell strategies of Ag recognition in a stratified immune system -- Dynamics of Peripheral regulatory and effector T cells competing for antigen presenting cells -- Mathematical models of the role of IL-2 in the interactions between helper and regulstory CD4+ T cells -- A Physicist's approach to immunology -- Timescales of the adaptive immune response -- Using mathematical models to explore the role of cytoxic T lymphocytes in HIV infection -- Viral immunity and persistence -- Index |
| Summary |
Mathematical immunology is in a period of rapid expansion and excitement. At recent meetings, a common language and research direction has emerged amongst a world-class group of scientists and mathematicians. Mathematical Models and Immune Cell Biology aims to communicate these new ideas to a wider audience. The reader will be exposed to a variety of tools and methods that go hand-in-hand with the immunological processes being modeled. This volume contains chapters, written by immunologists and mathematicians, on thymocytes, on T cell interactions, activation, proliferation and homeostasis, as well as on dendritic cells, B cells and germinal centers. Chapters are devoted to measurement and imaging methods and to HIV and viral infections |
| Analysis |
immunologie |
|
immunology |
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bioinformatics |
|
receptoren |
|
receptors |
|
biomedische wetenschappen |
|
biomedicine |
|
systeembiologie |
|
systems biology |
|
computational science |
|
Medicine (General) |
|
Geneeskunde (algemeen) |
| Bibliography |
Includes bibliographical references and index |
| Notes |
English |
|
Print version record |
| In |
Springer eBooks |
| Subject |
Immunology -- Mathematical models
|
|
Adaptive Immunity -- immunology
|
|
Models, Immunological
|
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B-Lymphocytes -- immunology
|
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T-Lymphocytes -- immunology
|
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Immunology -- Mathematical models
|
| Form |
Electronic book
|
| Author |
Molina-París, Carmen.
|
|
Lythe, Grant, 1966-
|
| LC no. |
2011926883 |
| ISBN |
9781441977250 |
|
1441977252 |
|
1441977244 |
|
9781441977243 |
|
