Description |
1 online resource |
Contents |
What is protein moonlighting and why is it important? / Constance J. Jeffery -- Exploring structure-function relationships in moonlighting proteins / Sayoni Das, Ishita Khan, Daisuke Kihara, Christine Orengo -- Overview of protein moonlighting in bacterial virulence / Brian Henderson -- Moonlighting proteins as cross-reactive autoantigens / Wim van Eden -- Chaperonin 60 paralogues in mycobacterium tuberculosis and tubercle formation / Brian Henderson -- Legionella pneumophila chaperonin 60 an extra- and intra-cellular moonlighting virulence-related factor / Karla N. Valenzuela-Valderas, Angela L. Riveroll, Peter Robertson, Lois E. Murray, and Rafael A. Garduño -- An overview of peptidylprolyl isomerases in bacterial virulence / Brian Henderson -- GAPDH : a multifunctional moonlighting protein in eukaryotes and prokaryotes / Michael A. Sirover -- Streptococcus pyogenes GAPDH : a cell surface major virulence determinant / Vijay Pancholi -- Group B streptococcus GAPDH and immune evasion / Paula Ferreira and Patrick Trieu-Cuot -- Mycobacterium tuberculosis cell surface gapdh functions as a transferrin receptor / Vishant M Borradia, Manoj Raje, Chaaya Iyengar -- Gapdh and probiotic organisms / Hideki Kinoshita -- Impact of streptococcal enolase in virulence / Marcus Fulde and Simone Bergmann -- Streptococcal enolase and immune evasion / Masaya Yamaguchi and Shigetada Kawabata -- Borrelia burgdorferi enolase and plasminogen binding / Catherine A. Brissette -- Triosephosphate isomerase from staphylococcus aureus and plasminogen receptors on microbial pathogens / Reiko Ikeda, Tomoe Ichikawa -- Moonlighting functions of bacterial fructose-1,6 bisphosphate-aldolases / Neil J Oldfield, Fariza Shams, Karl G Wooldridge and David PJ Turner -- Pyruvate dehydrogenase and plasminogen binding in mycoplasmas / Anne Gründel, Kathleen Friedrich, Melanie Pfeiffer, Enno Jacobs, Roger Dumke -- Unexpected interactions of leptospiral ef-tu proteins / Natalia Salazar and Angela Barbosa -- Mycobacterium tuberculosis antigen 85 family proteins : mycolyl transferases and matrix-binding adhesins / Christopher P. Ptak, Chih-Jung Kuo, and Yung-Fu Chang -- Miscellaneous il-1[beta]-binding proteins of aggregatibacter actinomycetemcomitans / Riikka Ihalin -- Bacteriophage moonlighting in the control of bacterial pathogenicity / Janine Bowring, Alberto Marina, José R. Penadés and Nuria Quiles-Puchalt -- Viral entry glycoproteins and viral immune evasion / Jonathan D. Cook and Jeffrey E. Lee |
Summary |
Moonlighting Proteins: Novel Virulence Factors in Bacterial Infections is a complete examination of the ways in which proteins with more than one unique biological action are able to serve as virulence factors in different bacteria. The book explores the pathogenicity of bacterial moonlighting proteins, demonstrating the plasticity of protein evolution as it relates to protein function and to bacterial communication. Highlighting the latest discoveries in the field, it details the approximately 70 known bacterial proteins with a moonlighting function related to a virulence phenomenon. Chapters describe the ways in which each moonlighting protein can function as such for a variety of bacterial pathogens and how individual bacteria can use more than one moonlighting protein as a virulence factor. The cutting-edge research contained here offers important insights into many topics, from bacterial colonization, virulence, and antibiotic resistance, to protein structure and the therapeutic potential of moonlighting proteins. Moonlighting Proteins: Novel Virulence Factors in Bacterial Infections will be of interest to researchers and graduate students in microbiology (specifically bacteriology), immunology, cell and molecular biology, biochemistry, pathology, and protein science |
Bibliography |
Includes bibliographical references and index |
Notes |
Print version record and CIP data provided by publisher |
Subject |
Bacterial diseases.
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Bacterial proteins.
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Bacterial Proteins -- physiology
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Virulence Factors
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Bacterial Infections
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Bacterial Proteins
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MEDICAL -- Forensic Medicine.
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MEDICAL -- Preventive Medicine.
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MEDICAL -- Public Health.
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Molecular Biology.
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Life Sciences.
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SCIENCE.
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Bacterial diseases
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Bacterial proteins
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Malalties bacterianes.
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Genre/Form |
Electronic books
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Llibres electrònics.
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Form |
Electronic book
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Author |
Henderson, Brian (Professor), editor.
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LC no. |
2016051302 |
ISBN |
9781118951132 |
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1118951131 |
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9781118951125 |
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1118951123 |
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9781118951149 |
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111895114X |
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