| Description |
1 online resource (xii, 265 pages) : illustrations |
| Contents |
1. Abdominal obesity, metabolic syndrome, and risk of cardiovascular disease / Jean-Pierre Despré︠s︡ and Vincenzo Di Marzo -- 2. Abdominal obesity in type 2 diabetes / Isabelle Lemieux and Jean-Pierre Després -- 3. Obesity and hypertension / Paul Poirier and Caroline Rhéaume -- 4. Visceral adiposity, liver fat, and atherogenic dyslipidemia / Marja-Riitta Taskinen, Martin Adiels, and Jan Borén -- 5. Visceral adiposity and inflammation / Ulf Smith -- 6. Abdominal obesity and alterations in haemostasis-thrombosis / Irène Juhan-Vague and Marie-Christine Alessi -- 7. Physiological and metabolic characteristics of visceral adipocytes / Alain Veilleux and André Tchernof -- 8. The endocrine function of adipose tissue : implications of visceral obesity for patients with cardiometabolic risk / Max Lafontan -- 9. Free fatty acid metabolism in visceral obesity / Asem Ali and Michael D. Jensen -- 10. Animal models of visceral obesity / Derek M. Huffman and Nir Barzilai -- 11. Insulin sensitivity and visceral adiposity : effects of rimonabant / Joyce M. Richey [and others] -- 12. Physical activity in the management of visceral obesity and related cardiometabolic risk / Peter M. Janiszewski and Robert Ross -- 13. Can we change the lifestyle of high-risk patients? Lessons from the prevention of diabetes trials / Jaakko Tuomilehto and Jaana Lindström -- 14. Can we change the body fat distribution phenotype? Lessons from PPAR agonists / Zubin Punthakee and Hertzel C. Gerstein -- 15. Is there an optimal diet for the management of abdominal obesity and related cardiometabolic risk / Benoît Lamarche and Caroline Richard -- 16. The EC system and central control of energy balance : the hypothalamus / Vincenzo Di Marzo -- 17. The EC system and central control of energy balance : the nucleus accumbens / Tim C. Kirkham -- 18. The EC system and the HPA axis / Daniela Cota -- 19. The EC system and gut-brain interactions relevant to satiety / Richard Jones, Galina Burdyga, David G. Thompson, and Graham J. Dockray -- 20. The endogenous cannabinoid system in the gastrointestinal tract / Angelo A. Izzo -- 21. The EC system in the adipose tissue and endocrine pancreas / Isabel Matias -- 22. The EC system in the immune system and the inflammatory response / Tracy A. Sherwood and Thomas W. Klein -- 23. The endocannabinoid system in the liver / Ariane Mallat and Sophie Lotersztajn -- 24. The endocannabinoid system and cardiovascular disease / Pál Pacher and George Kunos -- 25. The endocannabinoid system, energy expenditure, and thermogenesis / Luigi Bellocchio, Cristina Cervino, Valentina Vicennati, Renato Pasquali, and Uberto Pagotto -- 26. Effects of dietary fatty acids on endocannabinoid signaling in the brain and peripheral organs / Alvin Berger and Vincenzo Di Marzo -- 27. Endocannabinoid overactivity and abdominal obesity / Vincenzo Di Marzo and Jean-Pierre Després -- 28. CB1 antagonism in the management of abdominal obesity / Luc F. Van Gaal -- 29. Abdominal obesity and the endocannabinoid system CB1 blockade, insulin resistance, and type 2 diabetes / André J. Scheen -- 30. Abdominal obesity as a therapeutic target to manage the atherogenic dyslipidemia and related metabolic abnormalities / Jean-Pierre Després -- 31. CB1 blockade and hypertension / Luis M. Ruilope -- 32. Future developments 1 : CB1 blockade for weight gain subsequent to smoking cessation / Jaimee L. Heffner and Robert M. Anthenelli -- 33. Future developments 2 : cannabinoid CB1 receptor blockade in weight gain subsequent to psychiatric disorder treatment / Ester Fride, Shimon Rabichev, and Nikolai Gobshtis |
| Summary |
This internationally renowned author team provides a unique and thorough analysis and distillation of the endocannabinoid system and its relationship to abdominal obesity, diabetes, and cardiovascular disease. The endocannabinoid system (ECS) plays an important role in cardiometabolic risk, as well as modulating energy balance, feeding behavior, hepatic lipogenesis, and perhaps glucose homeostasis. Evidence suggests that the ECS is overactive in human obesity and dyslipidemia. Critical to the management of cardiometabolic risk, this new, timely book provides practical overviews and management guidance on many important topics |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Obesity -- Molecular aspects
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Abdomen.
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Cannabinoids.
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Cardiovascular system -- Diseases.
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Metabolic syndrome.
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Obesity -- complications
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Abdominal Fat
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Cardiovascular Diseases
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Endocannabinoids -- physiology
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Metabolic Syndrome
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Abdomen
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Cannabinoids
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MEDICAL -- Bariatrics.
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Metabolic syndrome
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Cardiovascular system -- Diseases
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Abdomen
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Cannabinoids
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| Form |
Electronic book
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| Author |
Després, Jean-Pierre
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Di Marzo, Vincenzo
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| ISBN |
1420060856 |
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9781420060850 |
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1281948810 |
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9781281948816 |
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