Title The complement factsbook / edited by Scott Barnum, Theresa Schein

Edition Second edition Published Oxford, United Kingdom : Academic Press, [2018]

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Description 1 online resource Contents [Introductory]: 1. Introduction / Scott R. Barnum, Theresa N. Schein -- 2. The complement system / Scott R. Barnum, Theresa N. Schein Part I: Collectins: 3. C1q / Berhane Ghebrehiwet -- 4. Mannose-binding lectin / Maciej Cedzyński, David C. Kilpatrick, Anna S. Świerzko -- 5. Ficolins / Misao Matsushita -- 6. The collectins / Katsuki Ohtani, Nobutaka Wakamiya Part II: Serine proteases: 7. MASP-1 / Ramus Pihl, Jens C. Jensenius, Steffen Thiel -- 8. MASP-2 / Ramus Pihl, Jens C. Jensenius, Steffen Thiel -- 9. MASP-3 / Ramus Pihl, Jens C. Jensenius, Steffen Thiel -- 10. C1r / Nicole M. Thielens, Christine Gaboriaud -- 11. C1s / Nicole M. Thielens, Christine Gaboriaud, Véronique Rossi -- 12. Factor D / Steven D. Podos, Atul Agarwal, Mingjun Huang -- 13. C2 / Kartik Manne, Sthanam V.L. Narayana -- 14. Factor B / Jennifer Laskowski, Joshua M. Thurman -- 15. Factor I / Marcin Okrój, Anna M. Blom Part III: C3 family: 16. C3 / Scott R. Barnum -- 17. C4 / David E. Isenman -- 18. C5 / Rick A. Wetsel Part IV: Terminal pathway components: 19. C6 / Richard G. DiScipio -- 20. C7 / Richard G. DiScipio -- 21. C8 / Richard G. DiScipio -- 22. C9 / Paul Morgan Part V: Regulatory proteins: 23. C1 inhibitor / Christian Drouet, Denise Ponard, Arije Ghannam -- 24. C4b-binding protein / Marcin Okrój, Anna M. Blom -- 25. Decay-accelerating factor / Joseph M. Christy, Christopher B. Toomey, David M. Cauvi, Kenneth M. Pollard -- 26. Membrane cofactor protein / M. Kathryn Liszewski, John P. Atkinson -- 27. Properdin / Viviana P. Ferreira -- 28. CR1 / Ionita Ghiran, Anne Nicholson-Weller -- 29. CRIg / Menno van Lookeren Campagne, Luz D. Orozco -- 30. Factor H and factor-H-like protein 1 / Paul N. Barlow -- 31. Factor-H-related proteins 1-5 / Scott R. Barnum, Paul N. Barlow -- 32. Clusterin / Valeria Naponelli, Saverio Bettuzzi -- 33. Vitronectin / Yu-Ching Su, Kristian Riesbeck -- 34. CD59 / Paul Morgan -- 35. CSMD1 / Scott R. Barnum Part VI: Anaphylatoxin and leucocyte receptors: 36. C3aR1 / Liam G. Coulthard, Owen A. Hawksworth, Trent M. Woodruff -- 37. C5aR1 / Liam G. Coulthard, Owen A. Hawksworth, Trent M. Woodruff -- 38. C5aR2 / Liam G. Coulthard, Owen A. Hawksworth, Trent M. Woodruff -- 39. C1q receptors / Suzanne Bohlson -- 40. CR2 / Susan A. Boackle -- 41. CR3 / Daniel C. Bullard -- 42. CR4 / Daniel C. Bullard -- Appendix A: Complement nomenclature 2014 / Claudia Kemper, Michael K. Pangburn, Zvi Fishelson Summary The Complement FactsBook, Second Edition, provides in-depth insights and an overview of the components of the complement system. This new edition highlights the use of newly recommended complement nomenclature, covering new pathways and proteins and adding information on mouse homologs. It is a completely revised and updated edition containing entries on all components of the complement system, and is an excellent source of one-stop shopping for complement information and references. It is the most convenient compilation of biochemical, biological and molecular biology for complementologists and those new in the field. This new edition is expanded to include relevant updates and topics that have evolved since the last edition was published, including C1q and Lectins, C3 Family, Serine Proteases, Serum Regulators of Complement Activation, Cell Surface Proteins, and Terminal Pathway Proteins. Domain Structure diagrams are incorporated to clearly illustrate the relationships between all the complement proteins, both within families and between families. Introduces complement function, simply described for each functionIncludes the cDNA sequences that are marked with intron/exon boundaries, facilitating genetic studiesPresents detailed structural information, including cDNA and gene structure for all proteinsIncorporates domain structures diagrams, which beautifully illustrate the relationship between all the complement proteins, both within, and between, families Notes Includes index Bibliography Includes bibliographical references and index Notes Vendor-supplied metadata Subject Complement (Immunology) Complement System Proteins -- genetics Base Sequence -- genetics Complement System Proteins HEALTH & FITNESS -- Diseases -- General. MEDICAL -- Clinical Medicine. MEDICAL -- Diseases. MEDICAL -- Evidence-Based Medicine. MEDICAL -- Internal Medicine. Complement (Immunology) Form Electronic book ISBN 9780128104217 012810421X 9780128104200 0128104201

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