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Title Mediastinal lesions : diagnostic pearls for interpretation of small biopsies and cytology / Anja C. Roden, Andre L. Moreira, editors
Published Cham, Switzerland : Springer, 2017


Description 1 online resource
Contents Preface; Acknowledgements; Contents; Contributors; 1 Introduction; References; 2 Mediastinal Biopsy Techniques; Introduction; Mediastinal Anatomic Considerations; Indications for Mediastinal Biopsies; Mediastinal Biopsy Techniques and Approaches; Conflict of Interest/Financial Relationships; References; 3 Radiologic Features of Mediastinal Lesions; Introduction; Classification of Mediastinal Compartments; General Considerations; Role of Imaging; Imaging Approach to Mediastinal Lesions; Fat-Containing Lesions; Teratoma; Thymolipoma; Lipoma and Liposarcoma; Cystic Lesions; Thymic Cyst; Teratoma
Pericardial CystBronchogenic Cyst; Esophageal Duplication Cyst; Meningocele; Soft Tissue Lesions; Thyroid Goiter; Thymic Epithelial Neoplasms; Lymphoma; Non-Teratomatous Germ Cell Tumors; Thymic Hyperplasia; Esophageal Neoplasms; Neurogenic Neoplasms; Miscellaneous Lesions; Paraspinal Abscess; Parathyroid Adenoma; Extramedullary Hematopoiesis; Take Home Message; References; 4 Cytologic Features of Mediastinal Lesions; Introduction; Thymoma: Challenges and Pitfalls; Thymoma Type A; Spindle Cell Carcinoid Tumor; Soft Tissue Tumors; Thymoma WHO Type B; Thymic Carcinoma; Carcinoid Tumors
Germ Cell TumorsSeminoma; Embryonal Carcinoma; Yolk Sac Tumor; Choriocarcinoma; Metastatic Carcinoma; Thymoma WHO Type B1; Lymphoma; Large B-Cell Lymphoma; Acute Lymphoblastic Lymphoma; Thymic Hyperplasia; Small Blue Cell Pattern; Ewing Sarcoma; Small Cell Carcinoma; Neuroblastoma; Immature Teratoma; Inflammatory Patterns; Granulomatous Infectious Diseases; Sarcoidosis; Hodgkin Lymphoma; Thymic Cysts; Mesothelial/Pericardial Cysts; Bronchogenic Cyst; Mature Teratoma; Cystic Thymoma; Major Pitfalls for the Cytological Diagnosis of Thymoma; References
5 Thymic Epithelial Tumors and Benign Thymic LesionsThymic Epithelial Tumors: Thymomas, Thymic Carcinomas, Neuroendocrine Tumors; Thymic Epithelial Tumors: Definition and Terminology; Tumor Heterogeneity, Proper Sampling, Reporting of Histology and Tumor Stage; Epidemiology; Etiology and Molecular Pathogenesis; Clinical Considerations; Problems with Small Biopsies and Biopsy Indications-General Considerations; Thymomas; Type A Thymoma, Including the "Atypical Type a Thymoma" Variant; Type AB Thymoma; Type B1 Thymoma; Type B2 Thymoma; Type B3 Thymoma
Micronodular Thymoma with Lymphoid Stroma (MNT)Metaplastic Thymoma (MPT); Rare Other Thymomas; Thymic Carcinomas (TCs); Thymic Squamous Cell Carcinoma (TSQCC); Basaloid Carcinomas; Lymphoepithelioma-Like Carcinoma (LELC); Mucoepidermoid Carcinoma; Clear Cell Carcinoma; Sarcomatoid Carcinoma; Adenocarcinoma; NUT Carcinoma; Undifferentiated Carcinoma; Other Rare Thymic Carcinomas; Neuroendocrine Tumors of the Thymus; Typical and Atypical Carcinoids; Large-Cell Neuroendocrine Carcinoma; Small-Cell Carcinoma; Thymic Hyperplasias; True Thymic Hyperplasia; Thymic Follicular Hyperplasia (TFH)
Summary This book addresses the current concepts in tissue acquisition, diagnosis, and classification of mediastinal lesions in small biopsies including cytology. Examples of mediastinal diseases that are either more common, more challenging to diagnose, or have a differential diagnosis that is important and might require different modes of treatment are highlighted. The knowledge of some key morphologic features and immunohistochemical pitfalls will be helpful for the practicing pathologist to tackle this challenge. The general workup of a mediastinal biopsy and the workup of major disease groups in mediastinal pathology which the general pathologist should be familiar with is discussed. Morphologic and, if applicable, immunophenotypic and molecular features that can help to distinguish these disease entities are highlighted. Furthermore, the reader will learn about the pertinent clinical implications of the diseases. Mediastinal Lesions: Diagnostic Pearls for Interpretation of Small Biopsies and Cytology will be a reference guide for pathologists, pathologists-in-training, and allied professionals, including oncologists, pulmonologists, surgeons, and radiologists
Notes Includes index
Bibliography Includes bibliographical references at the end of each chapters and index
Notes Online resource; title from PDF title page (SpringerLink, viewed May 31, 2017)
Subject Mediastinum -- Tumors -- Biopsy
Mediastinal Neoplasms -- pathology
Mediastinal Neoplasms -- diagnosis
Mediastinal Neoplasms -- therapy
HEALTH & FITNESS -- Diseases -- General.
MEDICAL -- Clinical Medicine.
MEDICAL -- Diseases.
MEDICAL -- Evidence-Based Medicine.
MEDICAL -- Internal Medicine.
Form Electronic book
Author Roden, Anja C., editor
Moreira, Andre L., editor
ISBN 9783319483795