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Title Bisphenol A : a multi-model endocrine disruptor / edited by Natalie R. Gassman
Published Lonson : Royal Society of Chemistry, [2022]

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Description 1 online resource
Series Issues in toxicology ; no. 43
Issues in toxicology ; 43.
Contents Intro -- Title -- Copyright -- Contents -- Chapter 1 Classical and Non-classical Estrogen Receptor Effects of Bisphenol A -- 1.1 Introduction -- 1.2 Mechanism of Estrogen Signaling -- 1.3 Estrogenic Assessment of Xenoestrogens, and the Case of Bisphenol A -- 1.4 BPA-mediated Effects via Classical Estrogen Receptors -- 1.5 BPA-mediated Effects via Non-classical ER -- 1.5.1 Non-genotropic ER Actions -- 1.5.2 Genotropic ER Actions -- 1.6 Conclusion -- Acknowledgements -- References -- Chapter 2 Genotoxicity and Mutagenicity of Bisphenol A -- 2.1 Introduction -- 2.2 In Vitro Studies
Acknowledgements -- References -- Chapter 4 Bisphenol A and Its Impact on Human Telomerase, Telomere Length and Cell Aging -- 4.1 The Human Immune System and Aging -- 4.2 Telomere Length and Telomerase Regulation in Human T Cells -- 4.3 Estrogen and Mechanisms of Action in Human Immune Cells -- 4.4 Bisphenol A Interference With the Human Immune Response -- 4.5 BPA Regulates Telomerase Activity and Telomere Length in Immune Cells -- 4.6 BPA, DNA Damage and Repair Response in Immune Cells -- 4.7 Conclusions -- Abbreviations -- References
Chapter 5 The Role of Bisphenol A in Development of Autoimmunity -- 5.1 Introduction -- 5.2 Pathophysiological Mechanisms of Autoimmunity Due to BPA Exposure -- 5.2.1 Direct Mechanisms of BPA Action on the Immune System -- 5.2.2 Indirect Mechanisms of BPA Action on Immunity -- 5.3 The Role of BPA in Autoimmune Diseases -- 5.3.1 Systemic (Non-organ-specific) Autoimmune Diseases -- 5.3.2 Organ-specific Autoimmune Diseases -- 5.4 Conclusion -- References -- Chapter 6 A Novel Model for the Estrogenic Action of BPA in Developing Brain Following Maternal Ingestion
Summary By compiling critical studies in BPA to build a broader understanding of this complex endocrine-disrupting chemical and its impact on the environment and human health, this book is an ideal resource for postgraduates and researchers in a range of disciplines from toxicology to epigenetics and cancer epidemiology
Notes Includes index
Online resource; title from digital title page (viewed on March 08, 2022)
Subject Bisphenol A -- Toxicology
Form Electronic book
Author Gassman, Natalie R., editor
ISBN 9781839166501
1839166509
9781839166495
1839166495